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- 2024
- Lionel Pereira receives Faculty of Science Graduate Student Excellence in Teaching Award
- Scientists develop tool to predict sepsis in apparently healthy newborns
- Dr. Lynne Quarmby, cool new discoveries about Watermelon Snow
- Dr. Valentin Jaumouill茅 and Dr. Amy Lee, Molecular Biology and Biochemistry researchers receive Michael Smith Health Research BC Scholar awards
- Dr. Ryan Morin has been honored with the Bernard and Francine Dorval Prize from the Canadian Cancer Society
- Verheyen Lab breakthrough identifies gene that may reverse Parkinson鈥檚 disease
- MBB researchers awarded $2 million in funding from the Canadian Institutes of Health Research
- Dr. Glen Tibbits honoured as Distinguished 丁香园AV Professor
- Reflecting on barriers and progress towards equity in science
- Royal Society of Canada bestows Dr. Vocadlo with country鈥檚 highest academic honour
- Decoding the genome to predict the clinical course of lymphomas
- 2023 Award for Excellence in Supervision: Esther Verheyen
- In a recent Nature Communications paper, the Audas lab demonstrates that proteins can act as microscopic thermometers to sense and respond to changing environmental conditions
- 2023
- Dr. Dustin King speaks to Molecular Cell about sustainability and molecular biology
- Science Advances paper by new MBB PhD, Casey Engstrom and Professor Lynne Quarmby uses satellites to study the impact of Watermelon Snow on glacier loss in North America
- Dr. Sathiyaseelan and team explore the expression and therapeutic target potential of cysteine protease ATG4 in pancreatic cancer
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Areas of interest
Autophagy is an intracellular recycling process that promotes stress adaptation and cell survival. Our research program explores the contributions of autophagy to proteostasis, normal development, and cancer progression with a focus on breast and pancreatic cancers. We are also investigating the therapeutic potential of autophagy modulation in these cancers.
Education
- B.Sc., Biology (honours), 丁香园AV
- M.Sc., Genetics, University of British Columbia
- Ph.D., Developmental Biology, Washington University School of Medicine, St. Louis, USA
Selected Publications
- Bosc D, Vezenkov L, Bortnik S, An J, Xu J, Choutka C, Hannigan AM, Kovacic S, Loo S, Clark PGK, Chen G, Guay-Ross RN, Yang K, Dragowska WH, Zhang F, Go NE, Leung A, Honson NS, Pfeifer TA, Gleave M, Bally M, Jones SJ, Gorski SM, Young RN. A new quinoline-based chemical probe inhibits the autophagy-related cysteine protease ATG4B. Scientific Reports. 2018; 8(1):11653. PMID: 30076329
- Xu J, Camfield R, Gorski SM. The interplay between exosomes and autophagy - partners in crime. Journal of Cell Science. 2018; 131(15). PMID: 30076239
- Choutka C, DeVorkin L, Go NE, Hou YC, Moradian A, Morin GB, Gorski SM. Hsp83 loss suppresses proteasomal activity resulting in an upregulation of caspase-dependent compensatory autophagy. Autophagy. 2017; 13(9):1573-1589. PMID: 28806103
- Bortnik S, Choutka C, Horlings HM, Leung S, Baker JH, Lebovitz C, Dragowska WH, Go NE, Bally MB, Minchinton AI, Gelmon KA, Gorski SM. Identification of breast cancer cell subtypes sensitive to ATG4B inhibition. Oncotarget. 2016; 7(41):66970-66988. PMID: 27556700
Courses
Spring 2025
Future courses may be subject to change.