- About
- People
- Faculty
- Tim Audas
- Christopher Beh
- Lorena Braid
- Fiona S.L. Brinkman
- Mark Brockman
- Jonathan Choy
- Lisa Craig
- Sharon Gorski
- Nicholas Harden
- Nancy Hawkins
- Robert Holt
- William Hsiao
- Valentin Jaumouill茅
- Lisa Julian
- Dustin King
- Irina Kovalyova
- Mani Larijani
- Amy Lee
- Michel Leroux
- Ryan Morin
- Ingrid Northwood
- Mark Paetzel
- Frederic Pio
- Lynne Quarmby
- Dheva Setiaputra
- Michael Silverman
- Sophie Sneddon
- Glen Tibbits
- Peter Unrau
- Esther Verheyen
- Stephanie Vlachos
- David Vocadlo
- Edgar Young
- Emeritus Faculty
- Associate Members
- Adjunct Faculty
- Research Personnel
- Graduate & Postdocs
- Staff
- Department Committees
- Faculty
- Undergraduate
- Prospective Students
- 丁香园AV & Transferring
- Degree Programs
- MBB Co-op Program
- Careers in Molecular Biology and Biochemistry
- Scholarships & Funding
- Student Stories
- Contact Us
- Current Students
- Advising
- Courses
- Degree Programs
- MBB Co-op Program
- Research Opportunities
- Scholarship & Funding
- Student Resources
- Prospective Students
- Graduate
- Prospective Students
- Current Students
- Manage Your Program
- Degree Requirements
- Courses
- Course Descriptions
- Course Offerings
- Spring (1241)
- Summer (1244)
- Fall (1247)
- Spring (1231)
- Summer (1234)
- Fall (1237)
- Spring (1221)
- Summer (1224)
- Fall (1227)
- Fall (1217)
- Summer (1214)
- Spring (1211)
- Fall (1207)
- Summer (1204)
- Spring (1201)
- Fall (1197)
- Summer (1194)
- Spring (1191)
- Fall (1187)
- Summer (1184)
- Spring (1181)
- Fall (1177)
- Summer (1174)
- Spring (1171)
- Fall (1167)
- Summer (1164)
- Spring (1161)
- Fall (1157)
- Summer (1154)
- Spring (1151)
- Funding and Awards
- Forms And Resources
- Events
- Graduate Student Caucus
- Research
- Research Labs
- Audas Lab
- Beh Lab
- Braid lab
- Brinkman Lab
- Brockman Lab
- Chen Lab
- Choy Lab
- Craig Lab
- Gorski Lab
- Harden Lab
- Hawkins Lab
- Holt Lab
- Hsiao Lab
- Jaumouill茅 Lab
- King Lab
- Larijani Lab
- Lee Lab
- Leroux Lab
- Morin Lab
- Paetzel Lab
- Pio Lab
- Quarmby Lab
- Sen Lab
- Setiaputra Lab
- Thewalt Lab
- Tibbits Lab
- Unrau Lab
- Verheyen Lab
- Vocadlo Lab
- Young Lab
- Bioinformatics & Genomics
- Cells & Disease
- Infection & Immunity
- Macromolecular Biochemistry
- Undergraduate Research Opportunities
- C2D2 Centre for Cell Biology, Development, and Disease
- Omics Data Science Initiative
- Recent Publications
- Research Labs
- Resources
- News & Events
- Seminars
- MBB Calendar
- Colloquia
- Honours & Awards
- News Archives
- 2024
- Dr. Ryan Morin has been honored with the Bernard and Francine Dorval Prize from the Canadian Cancer Society
- Royal Society of Canada bestows Dr. Vocadlo with country鈥檚 highest academic honour
- Verheyen Lab breakthrough identifies gene that may reverse Parkinson鈥檚 disease
- MBB researchers awarded $2 million in funding from the Canadian Institutes of Health Research
- Dr. Glen Tibbits honoured as Distinguished 丁香园AV Professor
- Decoding the genome to predict the clinical course of lymphomas
- Reflecting on barriers and progress towards equity in science
- 2023 Award for Excellence in Supervision: Esther Verheyen
- In a recent Nature Communications paper, the Audas lab demonstrates that proteins can act as microscopic thermometers to sense and respond to changing environmental conditions
- 2023
- Dr. Dustin King speaks to Molecular Cell about sustainability and molecular biology
- Science Advances paper by new MBB PhD, Casey Engstrom and Professor Lynne Quarmby uses satellites to study the impact of Watermelon Snow on glacier loss in North America
- Dr. Sathiyaseelan and team explore the expression and therapeutic target potential of cysteine protease ATG4 in pancreatic cancer
- 2022
- 2021
- 2020
- 2019
- 2018
- 2017
- 2016
- 2015
- 2024
- Science Rendezvous
- Support MBB
- Faculty + Staff Portal
Mark Paetzel
Professor
Molecular Biology & Biochemistry
Science
Areas of interest
Our lab uses molecular biology, protein chemistry, X-ray crystallography and other physical methods to investigate the structure and catalytic mechanism of enzymes. Currently we have many project related to viral protease self-processing, compartmentalized proteases, and eukaryotic membrane bound proteases.
Education
- A.A. (Theology), Golden Valley Lutheran College
- B.Sc. (Biology), Syracuse University
- B.Sc. (Chemistry), University of Minnesota
- Ph.D. (Chemistry), Ohio State University
Selected Publications
- Lee, J. et al. X-ray crystallographic characterization of the SARS-CoV-2 main protease polyprotein cleavage sites essential for viral processing and maturation.
- Lee et al. Crystallographic structure of wild-type SARS-CoV-2 main protease acyl-enzyme intermediate with physiological C-terminal autoprocessing site.
- Paetzel, M. Bacterial Signal Peptidases.
- View more publications
Important Notice
MSc and PhD Student Positions Available 鈥� THE NATURE OF BIOMOLECULES
The Paetzel lab currently has openings for MSc or PhD students.
Thesis projects are designed to suit your interests and strengths and vary from chemical to computational, from pathogen to host, and from basic research to applied research.
Please visit the to learn more and e-mail Dr. Paetzel (mpaetzel@sfu.ca) with transcripts and CV.
Courses
Future courses may be subject to change.