丁香园AV

Introduction

• 0.00.00 -0.00.15

Increasing Health Care Costs

The current costs of health care in the United States are outlined: knowledge blindspots cost the economy hundreds of billions of dollars.

• 0.00.16 - 0.02.00 : Increasing Number and Cost of Drugs
• 0.02.01 - 0.03.38 : Rising Cost of Health Care
• 0.03.39 - 0.05.00 : Solving the Wanamaker Problem in Health Care
• 0.05.01 - 0.07.58 : Current Knowledge Blindspots in Health Care
• 0.07.59 - 0.09.29 : Treating Patients as Averages
• 0.09.30 - 0.10.54 : Lecture Outline

Why Now? Changes in Data & Technology Throughout the Years

How datafication is increasing both the scope of health care data sources and pportunities to revolutionize the health care system.

• 0.10.55 - 0.11.47 : Traditional Health Care Data Sources
• 0.11.47 - 0.14.13 : New Health Care Data Sources
• 0.14.14 - 0.15.40 : Rise in Computing Power
• 0.15.41 - 0.16.39 : The Perfect Opportunity

GNS Healthcare

Colin Hill introduces his company, GNS Healthcare, and addresses how he plans to improve health outcomes with high-throughput precision health care.

• 0.16.40 - 0.18.59 : Founding GNS Healthcare
• 0.19.00 - 0.21.29 : Audience Question - Accessibility of Data
• 0.21.30 - 0.23.35 : Audience Question - Evolving Data Models
• 0.23.36 - 0.25.17 : GNS Healthcare in the Media
• 0.25.18 - 0.25.54 : GNS Healthcare Partners

Proprietary REFS Platform - Modelling & Machine Learning

REFS machine learning platform (that relies on 鈥渟upercomputing鈥� and 鈥渞egression on steroids鈥�) is introduced and explained.  Colin Hill responds to question regarding disparities in population health: will the benefits of complex (and potentially difficult to procure) precision medicine methods benefit only those already able to obtain the best health outcomes money can buy?

• 0.25.55 - 0.28.11 : Types of Data Analytics
• 0.28.12 - 0.29.14 : Machine Learning & Simulation - What if?
• 0.29.15 - 0.33.32 : GNS Healthcare Machine Learning Platform: REFS - Reverse Engineering Forward Simulation Algorithm
• 0.33.33 - 0.35.22 : Audience Question - Model Readout & Validation
• 0.35.23 - 0.36.44 : Audience Question - Genomic Data in Modelling
• 0.36.45 - 0.38.30 : Audience Question - Potential GNS Partnership
• 0.38.31 - 0.40.06 : Audience Question - Genomic Sequencing
• 0.40.07 - 0.44.42 : Audience Question - REFS Algorithms
• 0.44.43 - 0.52.28 : Audience Question - Disparities in Population Health exacerbated by Precision medicine?

Examples of GNS Healthcare Solutions

How REFS can reduce the cost of and improve the precision of treating metabolic syndrome.

• 0.52.29 - 0.53.54 : The Impact of GNS Causal Models
• 0.53.55 - 0.57.34 : Coronary Artery Disease
• 0.57.35 - 1.01.19 : Preterm Birth
• 1.01.20 - 1.07.11 : Metabolic Syndrome

What Happens if Precision Medicine Wins?

An ideal future, with a personalized treatment landscape available to individual patients facing debilitating disease.

• 1.07.12 - 1.08.52 : Personalized Treatment Landscape
• 1.08.53 - 1.10.04 : Can Big Data Save My Dad From Cancer?
• 1.10.05 - 1.13.49 : Transforming Medicine - The Elizabeth Kauffman Institute

Closing Remarks

• 1.13.50 - 1.14.50 : Thank You - Catherine Murray, Associate Dean, 丁香园AV Undergraduate Academic Programs & Enrolment Management
• 1.14.51 - 1.17.33 : Question from student host - Joseph Yeates, 丁香园AV Beedie School of Business
• 1.17.34 - 1.20.59 : Question from student host - Chandra Lebovitz, Doctoral Candidate, 丁香园AV Department of Molecular Biology and Biochemistry
• 1.21.00 - 1.22.14 : Gift Presentation - student host Joseph Yeates, 丁香园AV Beedie School of Business