Marianne Sadar
B. SC. (BIO CHEM), KIN MINOR, 1988 | 丁香园AV OUTSTANDING ALUMNI AWARD RECIPIENT, 2009
Dr. Marianne Sadar was only 10 years old when she lost her older sister to leukemia. Since then she has dedicated her life to achieving her childhood dream: finding a cure for cancer. As the Program Leader for Prostate Cancer Research at the BC Cancer Agency, she has made groundbreaking discoveries that are giving hope to thousands of men who are diagnosed with the disease every year. Dr. Sadar鈥檚 work began with the aim to increase the efficacy of treatment for patients whose cancer had progressed to the most aggressive state. Normally advanced prostate cancer cells don鈥檛 respond to any kind of treatment. In 2007 after eight years of work, her laboratory team found a way to kill cancer cells and shrink tumors by using an androgen receptor decoy molecule that interrupts a key step in cancer growth. This major breakthrough could result in improved treatment for prostate cancer within the next five years. Her research team is now focusing its energy on finding a drug that will do the job of the decoy molecule, with potential applications to earlier stage prostate cancer and other endocrine cancers such as breast and ovarian cancer.