Molecular Biology and Biochemistry Courses

Department of Molecular Biology and Biochemistry | Faculty of Science
丁香园AV Calendar 2012 Summer

The following are all the courses offered in this area. To view the current course catalog and/or course schedule on the Student Information System, visit (select "Class Search/Browse Schedule" on the left menu).

MBB 151-3 Practicum I

First term of work experience in the Molecular Biology and Biochemistry Co-operative Education Program. Units from this course do not count towards the units required for an 丁香园AV degree. Prerequisite: acceptance in the Science Co-operative Education Program.

MBB 201-3 Biochemistry of the Cell

An introduction to cellular processes with an emphasis on protein structure and function. Topics that will be explored include transcription, translation and protein synthesis, basic metabolic pathways, biomembranes, organelles, vesicle transport, the cytoskeleton and cell signaling. Prerequisite: BISC 101; CHEM 281 as prerequisite or corequisite.

MBB 222-3 Molecular Biology and Biochemistry

The structure, function and synthesis of proteins, RNA and DNA and their interrelated biological functions within the cell. An introduction to molecular biology techniques and methods of protein purification and analysis. Prerequisite: CHEM 281 with a grade of C- or better. Corequisite or prerequisite: CHEM 282 or 283.

MBB 231-3 Cellular Biology and Biochemistry

A study of the molecular processes which underlie cell structure and function, integrating ultrastructural, physiological and biochemical approaches. Modern techniques used in the analysis of organelle and cell function are integral parts of the course. Prerequisite: MBB 222, BISC 101 and CHEM 282 with grades of C- or better. Students may not receive credit for MBB 221 and MBB 231

MBB 242-3 Introductory Genomics

A broad introductory survey of the genome sciences including genome organization, whole genome sequencing, genomic variation in health and disease, comparative genomics, transcriptomes and proteomes and some applications of genomics. Workshops will introduce bioinformatic approaches to the use of genomic databases. Prerequisite: BISC 101, BISC 102, MBB 222 or permission of the department.

MBB 251-3 Practicum II

Second term of work experience in the Molecular Biology and Biochemistry Co-operative Education Program. Units from this course do not count towards the units required for an 丁香园AV degree. Prerequisite: acceptance in the Science Co-operative Education Program.

MBB 300-1 Special Topics in Biotechnology and Business

A survey of the legal, economic and social aspects of technology transfer in the areas of molecular biology, biochemistry, and biotechnology presented by a series of local experts. Topics will include patents, contracts, intellectual property, capitalization and others. The format will be a formal lecture followed by a workshop. Prerequisite: completion of the second year in the Molecular Biology and Biochemistry and Business Administration joint major or equivalent experience.

MBB 308-3 Molecular Biology Laboratory

Modern molecular biological and recombinant DNA methods such as DNA isolation, plasmid preparation, restriction enzyme digestion, Southern blots, cloning and polymerase chain reaction. Prerequisite: MBB 222, and MBB 221 or MBB 231, and MBB 331 as a co- or pre-requisite (the latter is recommended). Students with credit for BISC 357 may not take MBB 308 for further credit.

MBB 309W-4 Biochemistry Laboratory

Contemporary techniques in biochemistry including protein purification, immunochemical methods, and lipid characterization. Prerequisite: MBB 222, and MBB 221 or MBB 231. Recommended: CHEM 215 and CHEM 286 precede MBB 309. Writing.

MBB 321-3 Intermediary Metabolism

The enzymes and intermediates of major catabolic and anabolic pathways. Their regulation and integration in health and disease states. Prerequisite: MBB 222, and MBB 221 or MBB 231.

MBB 322-3 Molecular Physiology

Biochemical and molecular aspects of cellular function, interactions and communication including cell cycle, apoptosis, cancer, immune system, neuronal transmission and the signal transduction pathways that integrate them. Prerequisite: MBB 222, and MBB 221 or MBB 231.

MBB 323-3 Introduction to Physical Biochemistry

Introduction to physical biochemistry including rigorous treatment of thermodynamics and molecular transport and interactions with specific emphasis on biochemical and molecular biological processes. CHEM 360 may be substituted as an alternative to this requirement for MBB majors. Prerequisite: MATH 152 (or 155), PHYS 121 (or 102, or 126, or 141), CHEM 122 (or 102), MBB 222.

MBB 331-3 Molecular Biology

The study of DNA and RNA in relation to gene structure and expression: DNA replication and the regulation of gene expression in bacteria and higher organisms. Introduction to recombinant DNA and cloning theory; natural vector structures and recombinant vector construction. Prerequisite: MBB 222, and MBB 221 or MBB 231, BISC 202.

MBB 351-3 Practicum III

Third term of work experience in the Molecular Biology and Biochemistry Co-operative Education Program. Units from this course do not count towards the units required for an 丁香园AV degree. Prerequisite: acceptance in the Science Co-operative Education Program.

MBB 402-3 Molecular and Developmental Genetics

Selected aspects of developmental biology with an emphasis on genetic and molecular analyses in model systems such as Drosophilia, C. elegans and mice. The focus will be on signal transduction pathways and their regulation of developmental processes. Prerequisite: BISC 333 and MBB 331.

MBB 420-3 Selected Topics in Contemporary Biochemistry

The topics in this course will vary from term to term, depending on faculty availability and student interest. Prerequisite: will be announced before the start of the term and will depend upon the nature of the topic offered.

MBB 421-3 Nucleic Acids

Recent literature is examined for insights into the structure and properties of DNA and RNA, drawing on a variety of biochemical, chemical and molecular biological perspectives. Prerequisite: MBB 331.

MBB 422-3 Biomembranes

A review of recent research on the structure, dynamics, function and biosynthesis of membranes, membrane lipids and proteins. Prerequisite: MBB 322.

MBB 423-3 Protein Structure and Function

Recent research in transition state theory; specificity in enzyme catalyzed reactions, the use of recombinant DNA techniques to describe and modify enzyme catalysis, the function of enzymes in organic solvents, and the development of new catalytic activities through monoclonal antibody techniques. Prerequisite: two of MBB 321, 322, 323, 331.

MBB 424-3 Membrane Transport Mechanisms

Structure and function of molecules that mediate transport across membranes including channels, carriers, and pumps. Primary literature from the fields of biochemistry and physiology will be explored through lectures and independent study. Prerequisite: MBB 321, 322 and either MBB 323 or CHEM 360. Students who have taken MBB 420 under the same topic may not take this course for further credit.

MBB 426-4 Immune System I: Basis of Innate and Adaptive Immunity

The basic organization of the immune system, including structure, function and genetics of antibodies, T-cell receptors, innate immune receptors, and the complement system. Innate, antibody and cellular immune responses and their control, and development of the cells involved in these responses. Prerequisite: MBB 331. Students who have taken HSCI 325 or 426 cannot take MBB 426 for further credit.

MBB 427-3 Immune System II: Immune Responses in Health and Disease

The immunologic response to bacterial, viral and parasitic infections, immunological diseases, such as autoimmune diseases, immunodeficiency, hypersensitivity reactions (including asthma and allergy) and transplantation-rejection reactions. Immunotherapeutics and vaccine development. Prerequisite: MBB 426 or HSCI 426. MBB 427 is identical to HSCI 427 and students cannot receive credit for both courses.

MBB 428-3 Molecular Mechanisms of Microbial Pathogenesis

The molecular strategies that bacterial, viral and fungal pathogens use to colonize the human body and cause disease will be studied. Using specific organisms as illustrations, emphasis will be placed on the structural biology of molecular systems such as acquisition and use of virulence factors, adhesion to and invasion of host cells, secretion of toxins and immune escape. Prions, zoonoses and emerging diseases will be included. Prerequisite: MBB 322. Students who have taken MBB 420 under the same title cannot take this course for further credit.

MBB 430-3 Mechanisms of Secretory Transport

Analysis of mechanisms of protein, lipid, and nucleic acid delivery and transport within cells; processes of protein targeting, exocytosis, and endocytosis; molecular mechanisms of vesicle transport and membrane fusion; role in signal transduction and disease. Prerequisite: MBB 322 and MBB 331.

MBB 431-3 Cells and Disease

The cellular basis of selected chronic diseases such as cancer and polycystic kidney disease will be explored in-depth. Through the use of lectures and group discussions and an emphasis on the primary literature, the focus will be on recent developments in the study of these diseases. Prerequisite: MBB 322 and 331. Students who have taken MBB 440 under the same title cannot take this course for further credit.

MBB 432-3 Advanced Molecular Biology Techniques

Laboratory with accompanying lectures designed to give practical experience in advanced contemporary molecular biology techniques. Lab exercises will include site-directed mutagenesis, preparation and characterization of GST-fusion proteins, construction of transgenes and their expression in transgenic organisms, and use of the yeast two-hybrid assay to study protein-protein interactions. Prerequisite: MBB 308 and 331, or permission of instructor.

MBB 435-3 Genome Biology

The analysis of entire genomes of organisms has only been possible since 1995. This new area of study will be examined in detail with emphasis on current research. Prerequisite: MBB 331.

MBB 436-3 Gene Expression

Lectures and student presentations will cover the wide range of ways in which organisms (primarily eukaryotes) regulate gene expression along the pathway from DNA to protein. Prerequisite: MBB 331.

MBB 437-3 Signal Transduction

An investigation of how biochemistry, cell biology and genetics is used to study the diverse mechanisms used in cell signaling along with an exploration of how the various approaches to studying signal transduction complement each other. Prerequisite: MBB 321, MBB 322 and MBB 331.

MBB 438-3 Human Molecular Genetics

Recent advances in human molecular genetics including genome analysis, gene therapy, genetic testing, and studies of genetic disorders. Prerequisite: MBB 331.

MBB 440-3 Selected Topics in Contemporary Molecular Biology

The topics in this course will vary from term to term, depending on faculty availability and student interest. Prerequisite: will depend upon the nature of the topic offered. Corequisite: will depend upon the nature of the topic offered.

MBB 441-3 Bioinformatics

Lectures and hands-on instruction at the computer in the use of, and theory behind, bioinformatic software and algorithms for the analysis of macromolecular data. Prerequisite: MBB 331 and an introductory computer science course (e.g. CMPT 110 or 120), or equivalent.

MBB 442-3 Proteomics

Proteomics concerns the analysis of the entire complement of proteins expressed by an organism. This course will consider protein sequence alignment, sequence database scanning, classification of protein structures, prediction of protein structure and function, and evolution of protein function. Prerequisite: MBB 321 and MBB 322; an introductory computer course (e.g. CMPT 110 or 120), or equivalent.

MBB 443-3 Protein Biogenesis and Degradation

A consideration of protein biogenesis (folding, assembly, and targeting to cellular compartments), modification, and degradation, and their roles in protein and cellular function. Prerequisite: MBB 321 and MBB 322.

MBB 444-3 Developmental Neurobiology

Examination of recent literature on neuronal growth cones and axonal guidance. Cell cultural, biochemical, and molecular genetic approaches will be emphasized in assessing guidance cues. Prerequisite: MBB 331.

MBB 446-3 Cell Death and Cell Survival

An examination of various types of cell death and cell survival mechanisms and their relationship to disease with a focus on cancer and therapeutic strategies. Prerequisite: MBB 322 and 331, or permission of the instructor. Students who took MBB 440 with the same title may not take MBB 446 for credit.

MBB 451-3 Practicum IV

Fourth term of work experience in the Molecular Biology and Biochemistry Co-operative Education Program. Units from this course do not count towards the units required for an 丁香园AV degree. Prerequisite: acceptance in the Science Co-operative Education Program.

MBB 452-3 Practicum V

Fifth term of work experience in the Molecular Biology and Biochemistry Co-operative Education Program. Units from this course do not count towards the units required for an 丁香园AV degree. Prerequisite: acceptance in the Science Co-operative Education Program.

MBB 461-3 Comparative Genomics

Examination of the fundamentals of comparative genomics, identification and activity of functional elements in genomes, inter- and intra-species comparisons, relationship of genomic to phenotypic variation, and personalized genomics are among the topics to be explored. Comparison of genome data has impacts on medicine and many other fields of the life sciences. Prerequisite: MBB 331. Students who have completed MBB 440 Comparative Genomics may not complete this course for further credit.

MBB 462-3 Human Genomics

The organization of the human genome and the role of genomic variation in health and disease. Genomics and personalized medicine; intellectual property and privacy issues. Prerequisite: MBB 331 or permission of the instructor. Students with credit for MBB 440 with this same course title may not complete this course for further credit

MBB 481-5 Individual Study Semester - Research Design

Part 1 of 3-part honors degree program, the individual study semester (ISS). The ISS provides students with the opportunity to carry out full time laboratory research in molecular biology and biochemistry. The grade for MBB 481 encompasses the research design aspect of the ISS, consisting of a written proposal and final report. Prerequisite: enrolment in the MBB or Biological Physics Honors Program, a minimum 3.0 CGPA and 3.0 UDGPA and permission of the MBB department. Students may not receive credit for both MBB 481-5 and MBB 493-15. Corequisite: MBB 482-5 and MBB 483-5.

MBB 482-5 Individual Study Semester - Research Performance

Part 2 of a 3-part honors degree program, the individual study semester (ISS). The ISS provides students with the opportunity to carry out full time laboratory research in molecular biology and biochemistry. The grade for MBB 482 encompasses the research performance component of the ISS. Prerequisite: enrolment in the MBB or Biological Physics Honors Program, a minimum 3.0 CGPA and 3.0 UDGPA and permission of the MBB department. Students may not receive credit for both MBB 482-5 and MBB 493-15. Corequisite: MBB 481-5 and MBB 483-5.

MBB 483-5 Individual Study Semester - Research Reporting

Part 3 of a 3-part honors degree program, the individual study semester (ISS). The ISS provides students with the opportunity to carry out full time laboratory research in molecular biology and biochemistry. The grade for MBB 483 encompasses the research reporting component of the ISS. Prerequisite: enrolment in the MBB or Biological Physics Honors Program, a minimum 3.0 CGPA and 3.0 UDGPA and permission of the MBB department. Students may not receive credit for both MBB 483-5 and MBB 493-15. Corequisite: MBB 481-5 and MBB 482-5.

MBB 490-2 Directed Study in Advanced Topics Biochemistry

Directed reading in a topic of molecular biology or biochemistry chosen in consultation with a supervisor. Before seeking approval for enrolment in this course, the student should have already obtained the agreement of a faculty member that he/she is willing to supervise the project, and have prepared a written proposal (of approximately one page) stating the nature of the directed reading topic. The course will include the preparation of a written term paper on the topic chosen. Prerequisite: MBB 222, and MBB 221 or MBB 231 and permission of the molecular biology and biochemistry department. Usually, upper level standing with at least 60 units in a Biochemistry major, minor or honors program will be required.

MBB 491-5 Undergraduate Research

Part time laboratory research in an area of molecular biology or biochemistry for preparation of a thesis in molecular biology and biochemistry. Before seeking approval for enrolment in this course, the student should already have obtained the agreement of a 丁香园AV faculty member that he/she is willing to supervise the project, and have prepared a written proposal (of approximately 1-2 pages) stating the nature of the research project. The course will include the preparation of a written research report on the results of the project, and may also, at the discretion of the supervisor, include an oral presentation of the results. Prerequisite: MBB 222, and MBB 221 or MBB 231 and permission of the molecular biology and biochemistry department. Usually, upper level standing with at least 60 units in a molecular biology and biochemistry major, minor or honors program will be required.

MBB 492-10 Individual Study Semester (Option A)

Full time laboratory research in an area of molecular biology or biochemistry for preparation of a thesis for the honors degree in molecular biology and biochemistry. This course is available to honors students who have already taken MBB 491 (or BICH 491-5), or who plan to break an individual studies project into two terms (see below). The course will include the preparation of a comprehensive written research report on the results of the project, and may also, at the discretion of the supervisor, include an oral presentation of the results. Prerequisite: permission of the department. Students with credit for BICH 492 may not take MBB 492 for further credit.

MBB 496-6 Joint Honors Undergraduate Directed Readings and Research

Directed reading and part-time scientific research in an area of molecular biology or biochemistry. This course is intended only for those students taking a joint MBB/BUS or MBB/CS honors degree. Before seeking approval for enrolment in this course, the student should already have obtained the agreement of a faculty member that he/she is willing to supervise the project, and have prepared a written proposal (of approximately 1-2 pages) stating the nature of the research readings and project. The course will include preparation of a written report on the results of the project, and may, at the discretion of the supervisor, include an oral presentation of the results. Prerequisite: 75 units and upper division standing in an MBB joint honors program, and MBB 308. Students who take MBB 496 are not allowed to take MBB 491, 492 or 493 with the same faculty supervisor.

MBB 505-3 Problem Based Learning in Bioinformatics

The problem-based learning course will develop students' ability to exchange ideas in small groups focused on real but simplified problems in bioinformatics. Problems will be carefully selected to cover multiple areas of bioinformatics research. This is an advanced bioinformatics course that assumes the student has previous bioinformatics training. Prerequisite: MBB 841 or equivalent bioinformatics course (undergraduate or graduate). This course is identical to CMPT 505 and students can not take both courses for credit.

MBB 506-3 Critical Research Analysis

Advanced seminar series for bioinformatics. Prerequisites: enrolment in Graduate Diploma in Bioinformatics. This course is identical to CMPT 506 and students cannot take both courses for credit.

MBB 566-3 Host-Microbe Interactions

Infectious pathogens (viruses, bacteria, fungi, protozoa, helminths), their life cycle including vectors of transmission, the biological mechanisms by which they establish infection and cause disease in humans. Pathogenic and protective aspects of the human response to infection; roles of vaccines and chemotherapy in reducing disease transmission. Impact of environmental, ecological and social/behavioral factors, including health-care financing and policy, on the host-pathogen relationship. Prerequisite: admission to the graduate program, or permission of the instructor.

MBB 611-6 Research Rotation I

One term of original bioinformatics research conducted in the lab of a designated mentor. Students are required to write their results in a scientific journal format and defend these results before a panel consisting of the project mentor plus two other qualified faculty members. Prerequisite: Enrolment in Graduate Diploma in Bioinformatics. This course is identical to CMPT 611 and students can not receive credit for both courses.

MBB 612-6 Research Rotation II

One term of original bioinformatics research conducted in the lab of a designated mentor. Students are required to write their results in a scientific journal format and defend these results before a panel consisting of the project mentor plus two other qualified faculty members. Prerequisite: enrolment in Graduate Diploma in Bioinformatics. This course is identical to CMPT 612 and students cannot receive credit for both courses.

MBB 613-6 Research Rotation III

One term of original bioinformatics research conducted in the lab of a designated mentor. Students are required to write their results in a scientific journal format and defend these results before a panel consisting of the project mentor plus two other qualified faculty members. Prerequisites: Enrolment in Graduate Diploma in Bioinformatics. This course is identical to CMPT 613 and students can not receive credit for both courses.

MBB 659-3 Special Topics in Bioinformatics

Consideration of recent research literature on contemporary topics in bioinformatics. Prerequisites: MBB 441 or 841; or CMPT 341 or 881.

MBB 669-3 Special Topics in Genomics

Consideration of recent research literature on contemporary topics in genomics. Prerequisites: MBB 435 or 835.

MBB 679-3 Special Topics in Proteomics

Consideration of recent research literature on contemporary topics in proteomics. Prerequisites: MBB 442 or 842.

MBB 721-3 Nucleic Acids

An examination of recent literature about the structure and function of DNA and RNA.

MBB 722-3 Biological Membranes

A review of recent literature on the structure, dynamics, function and biosynthesis of membrane lipids and proteins.

MBB 723-3 Protein Structure and Function

Transition state theory; specificity in enzyme catalyzed reactions; use of recombinant DNA techniques to describe and modify enzyme catalysis, catalytic activities through monoclonal antibody techniques.

MBB 724-3 Membrane Transport Mechanisms

MBB 726-4 The Immune System I: Basis of Innate and Adaptive Immunity

The basic organization of the immune system, including structure, function and genetics of antibodies, T-cell receptors, innate immune receptors, and the complement system. Innate, antibody and cellular immune responses and their control, and development of the cells involved in these responses. Prerequisite: MBB 331 or permission of the instructor. Students with credit for MBB or HSCI 426, MBB 826 or HSCI 726 may not complete MBB 726 for credit.

MBB 727-3 Immune System II: Immune Responses in Health and Disease

MBB 730-3 Mechanisms of Secretory Transport

Analysis of mechanisms of protein, lipid, and nucleic acid delivery and transport within cells. The course will examine processes of protein targeting, exocytosis, and endocytosis; molecular mechanisms of COP-and clathrin-mediated vesicle transport; and viral and SNARE-mediated membrane fusion. Lectures will present landmark experiments from classic papers, and student presentations will focus on recent research articles. The significance of these findings with respect to human disease and signal transduction will be considered. Prerequisite: MBB 322 and BISC 331/MBB 331 or permission of the instructor.

MBB 736-3 Gene Expression

A consideration of the mechanisms and regulation of gene expression in eukaryotes and prokaryotes.

MBB 737-3 Molecular Genetics of Signal Transduction

Consideration of recent literature dealing with mechanisms of signal transduction. The emphasis of the course varies from term to term. Past offerings have ranged from a specific focus on studying signaling using molecular genetics in model organisms, to an examination of diverse cell biological, biochemical, and genetic approaches being used in current signal transduction research.

MBB 738-3 Human Molecular Genetics

The course will consider recent advances in human molecular genetics. Topics will include genome analysis, genetic testing, and studies of genetic disorders. Prerequisite: MBB 331 (or BISC 331) or equivalent.

MBB 741-3 Bioinformatics

An overview of the newly emerging field of bioinformatics, which is loosely defined as the intersection between the fields of molecular biology and computer science. A combination of lecture format and hands-on instruction is provided in the use of, and theory behind, bioinformatic software tools used in genomic and computational biology research. An introduction to the development of bioinformatic software is included, though only basic computer science knowledge is required for this particular course. Prerequisite: one introductory computer programming course (e.g. CMPT 102, 103, 110, 120 or equivalent).

MBB 742-3 Proteomics

Since the completion of the human genome, the next step is to understand the function of these genes. Proteomics cover the integration of a number of topics with the aim of analyzing the complete complement of proteins expressed by a biological system. This course will give a general understanding of the proteome, describe many of the different aspects of proteomics that have been developed recently, identify the technologic limitations related to proteomics, and will also include likely future directions for the field. Prerequisite: one introductory computer programming course (e.g. CMPT 102, 103, 110, 120 or equivalent).

MBB 743-3 Protein Biogenesis, Function and Degradation

The central dogma of molecular biology (DNA to RNA to protein) underscores two fundamental biological processes, transcription and translation, that are essential to life. Protein biogenesis (folding, assembly, targeting to the proper cellular compartment), protein modification and protein degradation represent three other equally important cellular activities. The emphasis in this course will be to review the literature on protein biogenesis, function, and degradation, and explore the new and exciting developments that are just starting to uncover how mechanistically complex these processes are.

MBB 744-3 Developmental Neurobiology

The course will examine recent literature on neuronal growth cones and axonal guidance. Cell cultural, biochemical, and molecular genetic approaches will be emphasized in assessing the roles and functions of guidance cues. Prerequisite: MBB/BISC 331 and BISC 333 or equivalent and permission of the instructor.

MBB 746-3 Cell Death and Cell Survival

An examination of various types of cell death and cell survival mechanisms and their relationship to disease with a focus on cancer and therapeutic strategies.

MBB 761-3 Comparative Genomics

MBB 762-3 Human Genomics

The organization of the human genome and the role of genomic variation in health and disease. Genomics and personalized medicine; intellectual property and privacy issues.

MBB 801-3 Student Seminar in Molecular Biology and Biochemistry I

Discussion of recent literature through student seminars and written reports. Introduction to professional skills for scientific careers.

MBB 802-3 Student Seminar in Molecular Biology and Biochemistry II

Discussion of recent literature through student seminars and written reports. Introduction to professional skills for scientific careers. Prerequisite: MBB 801 or an MSc degree.

MBB 806-3 PhD Graduate Research Seminar

Oral presentation and defense of a written PhD research proposal. Students will be examined on their progress and grasp of knowledge relevant to the proposed research and their capacity to complete the proposed thesis research. Open only to students in the PhD molecular biology and biochemistry graduate program.

MBB 811-1 Techniques in Molecular Biology and Biochemistry

Consideration of methods applied to research in molecular, cellular, and developmental biology; genetics; and biochemistry. Can be repeated with permission of the instructor.

MBB 812-2 Techniques in Molecular Biology and Biochemistry

Consideration of methods applied to research in molecular, cellular, and developmental biology; genetics; and biochemistry. Can be repeated with permission of the instructor.

MBB 813-3 Techniques in Molecular Biology and Biochemistry

Consideration of methods applied to research in molecular, cellular, and developmental biology; genetics; and biochemistry. Can be repeated with permission of the instructor.

MBB 821-1 Cell and Molecular Biology Colloquium

Recent research articles on the molecular mechanisms underlying cellular activities will be presented and discussed by students and faculty, with an emphasis on critical analysis of the concepts and experimental design and methods. Prerequisite: BISC 331/MBB 331 or equivalent. Students who have taken BISC 821, 822 or 823 may not receive credit for this course. A student may not take more than 3 units of Cell and Molecular Biology Colloquium courses, including BISC 821, 822, 823.

MBB 822-1 Cell and Molecular Biology Colloquium

MBB 823-1 Cell and Molecular Biology Colloquium

MBB 824-3 Physical Biochemistry

The physical properties of biomacromolecules; modern physical methods applied to biomolecules; properties and analysis of membrane systems.

MBB 825-3 Bioenergetics

Consideration of important processes for biological energy transduction. Structure/function relationships of membrane components and other interacting macromolecular systems. Cannot be taken for credit in addition to CHEM 825.

MBB 827-3 Mechanisms in Enzyme Catalysis

The study of enzyme mechanisms by a variety of techniques including spectroscopic, kinetic, radioisotopic exchange, and site-directed mutagenesis.

MBB 828-3 Spectroscopic Methods in Biochemistry

Application of spectroscopic methods including multidimensional NMR, fluorescence, circular dichroism, and FTIR for determination of biomacromolecular structure. Includes elements of protein conformation.

MBB 829-3 Special Topics in Biochemistry

Consideration of recent literature concerning selected contemporary research topics. Can be taken more than once with permission of the instructor.

MBB 831-3 Molecular Evolution of Eukaryote Genomes

Examination of the dynamics of change in eukaryotic nuclear, mitochondrial, and chloroplast genome structure and organization.

MBB 832-3 Molecular Phylogeny and Evolution

Examination of the basic methods applicable to analyses of molecular phylogeny and evolution.

MBB 833-3 Developmental Genetics

Selected topics in the developmental genetics of drosophila.

MBB 834-3 Topics in Developmental Biology

Selected topics including pattern formation, morphogenetic determinants, inductive interactions, and differential gene expression in embryos.

MBB 835-3 Genome Analysis

Consideration of topics related to the structure and function of the genome with emphasis on genome mapping and sequencing projects, and computational methods for genomic sequence analysis.

MBB 839-3 Special Topics in Molecular Biology

Consideration of recent literature concerning selected contemporary research topics. Can be taken more than once with permission of instructor.

MBB 861-1 Biomolecular Structure and Function Colloquium

Recent research articles on the structure, function, and interactions of macromolecules including proteins, nucleic acids, and lipids, as well as their complexes, will be presented and discussed by students and faculty, with an emphasis on critical analysis of the concepts and experimental design and methods. Prerequisite: BISC 331/MBB 331 or equivalent.

MBB 862-1 Biomolecular Structure and Function Colloquium

MBB 863-1 Biomolecular Structure and Function Colloquium

Recent research articles on the structure, function, and interactions of macromolecules including proteins, nucleic acids, and lipids, as well as their complexes, will be presented and discussed by students and facuty, with an emphasis on critical analysis of the concepts and experimental design and methods. Prerequisite: BISC 331/MBB 331 or equivalent.

MBB 871-1 Directed Readings in Molecular Biology and Biochemistry

Programs of directed reading and critical discussions offered by faculty or staff members to individual students according to their needs. Study programs must be approved by the molecular biology and biochemistry graduate studies committee.

MBB 872-2 Directed Readings in Molecular Biology and Biochemistry

MBB 873-3 Directed Readings in Molecular Biology and Biochemistry

MBB 898-6 MSc Thesis

MBB 899-6 PhD Thesis

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