丁香园AV

Faculty of Health Sciences
丁香园AV Calendar 2012 Fall

The following are all the courses offered in this area. To view the current course catalog and/or course schedule on the Student Information System, visit (select "Class Search/Browse Catalog" on the left menu).

HSCI 100-3 Human Biology

An examination of the biological processes that underlie human health and well-being, with emphasis on the evolutionary and ecological influences affecting human populations. Students with credit for BISC 101 and 102 may not take HSCI 100 for further credit. Breadth - Science.

HSCI 120-3 Introduction to Human Sexuality and Sexual Behavior

Introductory information about human sexuality across a broad spectrum of topic areas. Sexual function is a fundamental part of a full and healthy life, but misinformation, concerns, problems, and dysfunctions are prevalent. An evidence-based introduction to human sexual function and dysfunction, and normal psychosexual development across a range of sexual behaviors. A perspective on the effects of socialization on sexual attitudes and behavior. Breadth-Social Sciences.

HSCI 130-4 Foundations of Health Science

How health, illness and disease are defined and measured for individuals and populations. Research strategies used to identify how health, illness and disease are distributed across human populations and how environmental, socio-economic, demographic, biological, behavioural and political factors influence individual and population health.

HSCI 140-3 Complementary and Alternative Medicine

A scientific, critical, and evidence-based examination of integrative, complementary, and alternative approaches to health. Why so many people are skeptical of conventional medicine and contemporary treatment modalities. Incorporation of traditional medicines into mainstream medicine. the need to investigate, and to protect the public from fraud. The extent to which both complementary and mainstream medicine can withstand the scrutiny of an evidence-based approach. Breadth-Social Sciences.

HSCI 150-3 Current Topics in Human Sexuality

Current issues and controversies and their impact on the sexual behaviour and well-being of individuals at different ages and circumstances. Typical topics might include sexually transmitted diseases and AIDS, sexual orientation and cultural differences in tolerance, abuses of power, and sexually explicit media. Differing perspectives and a diversity of views will be presented in a non-prescriptive manner. As a result, many of the opinions expressed in this course will be controversial.

HSCI 160-3 Global Perspectives on Health

An introduction to the differences in health and health services among the nations of the globe. Vulnerable sub-populations worldwide and their special health needs. Mechanisms whereby events in one country can impact health in another. Future worldwide health risks, their economic and health consequences. SARS, avian 'flu,' West Nile virus, 'mad cow disease,' antibiotic resistant malaria or tuberculosis. Dangers to rich and poor nations from ignoring health problems in developing world. Breadth-Social Sciences.

HSCI 170-3 Working for Health

Concepts including professionalism, professional ethics, interdisciplinarity, and knowledge translation will be explored along with types of health-related work, components of health care systems and public health, and workforce trends and tensions in Canada and internationally. Writing skills will be emphasized.

HSCI 180-3 Drugs and Society

Substance use within societies. Licit and illicit drug pharmacology, drug effects, risk factors, opportunities for intervention, drug policies and their implementation, and populations with unique vulnerabilities or needs. Major theories of substance use and addiction. Strengths and limitations of alternative approaches to managing substance use as a component of public health in Canada and globally.

HSCI 199-3 Special Topics in Health Sciences

A specific topic in health sciences which is not otherwise covered in-depth in regular courses. Prerequisite: will vary according to topic. Corequisite: will vary according to topic.

HSCI 211-3 Perspectives on Cancer, Cardiovascular, and Metabolic Diseases

An interdisciplinary overview of the major non-communicable diseases - cancers, cardiovascular and metabolic diseases - from a public health perspective. Review of biological mechanisms, risk factors, historical and cultural contexts, and global distribution. Prerequisite: HSCI 100 or BISC 101, HSCI 130.

HSCI 212-3 Perspectives on Infectious and Immunological Diseases

An integrated survey of infectious diseases and their social and economic causes and consequences. Infectious agents, including bacteria, protozoa, fungi and viruses -- how they spread, how they work, and how they can be stopped. Surveillance, prevention, and management of infectious diseases and epidemics. Prerequisite: HSCI 100 or BISC 101, HSCI 130.

HSCI 214-3 Perspectives on Mental Health and Illness

An interdisciplinary overview of mental health and mental illness among populations. A review of the distribution and risk factors of mental illnesses as well as the historical and cultural context of their development. Prerequisite: HSCI 100 or BISC 101, HSCI 130.

HSCI 215-3 Perspectives on Disability and Injury

An interdisciplinary overview of injury and disability. Review of global distribution and risk factors. Examination of disability and injury across multiple levels of analysis. Prerequisite: HSCI 100 or BISC 101, HSCI 130.

HSCI 216-3 Ecological Determinants of Human Growth, Development and Health

Effects that social and ecological factors have on human growth, development and health. Challenges such as epidemics, natural catastrophes, industrialization, globalization, migration, poverty, war, global warming, etc, leading to evolution and adaptations. Relationships between socio-ecological challenges, their health consequences and related gene-population variations and effects on growth, development, sexual maturation, reproductive investment, and senescence and health. Prerequisite: HSCI 100 or BISC 101.

HSCI 304-3 Perspectives on Environmental Health

Environmental risks and the impact of human activity on health. Chemical and biological hazards. Methodological approaches to their detection, assessment, management, and mitigation. Prerequisite: two HSCI 200-level courses one of which may be taken concurrently.

HSCI 305-3 The Canadian Health System

A comparative analysis of the Canadian health care financing and delivery systems and policies. History, organizational principles, health care resources, costs, access to care, quality, and equity. Societal and political issues, threats and values that affect Canada's health care system and others around the world. Prerequisite: 60 units, including nine HSCI units.

HSCI 306-3 Principles of Health Economics

A study of micro- and macro-economic concepts used in the pursuit of better health and health care. Choices within limited resources, economic evaluation of efficiency, equity, elasticity of health systems, policy and regulatory issues. Prerequisite: two HSCI 200-level courses one of which may be taken concurrently.

HSCI 307-3 Research Methods in Health Sciences

Principles and applications in health sciences research methodology. Quantitative and qualitative methods. Research process and design. Appropriate approaches for diverse research questions. Research ethics, sources of data, sampling, measurement, data collection, initial data analysis techniques. Prerequisite: two HSCI 200 division courses, one of which may be taken concurrently.

HSCI 308-3 Sickness and Wealth: Health in Global Perspective

New formations of wealth and power that contribute to international health disparities and consideration of the relations of power both between and within nation-states that make some people sick and keep others well. Economic and political collusions that make people sick. Infectious disease and child survival, health implications of war, biotech, and the politics of food and water. Prerequisite: 45 units. Recommended: HSCI 130.

HSCI 309-3 Health and the Built Environment

Relationships between the physical environment in which people live and their health and well being. How the built environment affects physical activity, obesity, exposure to pathogens and toxins, health status, mental health, and risk of illness and injury. How urban form, physical infrastructure, and landscape and building design can promote health. Prerequisite: 60 units including one HSCI course. Students with credit for HSCI 403 may not complete this course for credit

HSCI 312-3 Health Promotion: Individuals and Communities

Theoretical frameworks and their applications in health promotion and disease prevention. The development, implementation, and evaluation of programs aimed at individuals and communities in Canada and globally. Prerequisite: 60 units, including either HSCI 130 or KIN 140. Students who have completed HSCI 401 prior to fall 2010 may not receive credit for this course.

HSCI 319W-3 Applied Health Ethics

Practical ethical and legal issues in health sciences, emphasizing population and public health. Case studies approach highlighting current ethical dilemmas and decision-making in the context of global to local legal frameworks. Prerequisite: 45 units including nine HSCI units, one of which must be a 200 division course. HSCI 319 is identical to PHIL 319 and students cannot receive credit for both courses. Writing

HSCI 321-3 Human Pathophysiology

Molecular, cellular and systemic approach to examine topics in human pathophysiology. Prerequisite: MBB 231, or permission of the instructor.

HSCI 323-3 Principles of Pharmacology and Toxicology

Biological, molecular and biochemical actions of drugs and toxicants. Genetic and environmental risk determinants. Understanding the broad spectrum of toxicological problems encountered in clinical practice, drug development and regulation, and medical research. Prerequisite: MBB 231, CHEM 282.

HSCI 324-3 Human Population Genetics and Evolution

Human variation and human health in the context of population genetics, epidemiology, demography, and human evolution. Prerequisite: BISC 202.

HSCI 327-3 Global Health Ethics

Ethical issues related to public health as they are located in and influenced by a global context. Consideration of several ethical approaches including utilitarianism, deontic ethics, and the capabilities approach, as well as theories of justice. Application of approaches to topics ranging from global markets in human organs to international migration of health workers and pharmaceutical testing in the Developing World. Prerequisite: 60 units of completed course work and PHIL 120 or HSCI 319W. Students who have taken HSCI 320 or PHIL 327 may not take this course for further credit.

HSCI 329-3 Exploitation and Vulnerable Populations

Competing understandings of the moral wrong of exploitation. Application to practices and relationships that are the focus of concern over exploitation in the context of public and population health. Prerequisite: PHIL 120W or HSCI 319W or PHIL 319W, or permission from the instructor.

HSCI 330-3 Exploratory Strategies in Epidemiology

The concepts and measurements of human population dynamics in epidemiological inference. Identification of causes and prevalence of disease. Demographic and molecular methodology to assess the determinants of health and disease. Prerequisite: nine HSCI units including one HSCI 200 division course and either STAT 302 or 305 which may be taken concurrently.

HSCI 338-3 Animal Virology

Animal virology in the context of viral diseases in humans and animals. Animal viruses, their replication, virus-host interactions and viral diseases. Prerequisite: MBB 222 or permission of the instructor. Corequisite: BISC 303.

HSCI 340-3 Social Determinants of Health

Social determinants of health and health inequities. Explores how and why the social advantages and disadvantages that people experience - based on their social position(s) and social circumstances - determine their health status and overall well-being. Prerequisite: 60 units and two HSCI 200-level courses, one of which may be taken concurrently.

HSCI 350-3 Co-op Practicum I

First term of work experience in the Health Sciences Co-operative Education Program. Units from this course do not count towards the units required for an 丁香园AV degree. Work terms are graded as Pass/Fail. Prerequisite: students must be accepted into the Health Sciences Co-op program and complete Bridging Online.

HSCI 351-3 Co-op Practicum II

Second term of work experience in the Health Sciences Co-operative Education Program. Units from this course do not count towards the units required for an 丁香园AV degree. Work terms are graded as Pass/Fail. Prerequisite: completion of HSCI 350 Co-op Practicum I.

HSCI 371-2 Special Topics in Health Sciences

A specific topic in health sciences which is not otherwise covered in depth in regular courses. Prerequisite/Corequisite: will vary according to topic.

HSCI 372-3 Special Topics in Health Sciences

A specific topic in health sciences which is not otherwise covered in depth in regular courses. Prerequisite/Corequisite: will vary according to topic.

HSCI 373-4 Special Topics in Health Sciences

A specific topic in health sciences which is not otherwise covered in depth in regular courses. Prerequisite/Corequisite: will vary according to topic.

HSCI 399-3 Special Topics in Health Sciences II

A specific topic in health sciences which is not otherwise covered in depth in regular courses. Prerequisite/Corequisite: will vary according to topic.

HSCI 402-3 Substance Use and Addiction

Substance use and addiction within the context of public health. Determinants of substance abuse and dependence; varieties of substances and their associated health implication; compulsive and addictive behaviors; treatment approaches and their effectiveness for populations and groups; models of prevention; life-cycle and developmental considerations; identified populations; policies for prevention and control. Prerequisite: HSCI 214.

HSCI 404-3 Public Policy and Health Systems

Major public policy issues affecting Canadian and international health care systems. How the public policy process affects financing, delivery, and regulation of health programs and services. Theories of policy development in the health sector. Evaluation of the extent to which evidence influences policy decisions. Controversies, including: finance, regulatory issue, system restructuring, models of governance, public vs. private service delivery and resource allocation. Prerequisite: 60 units including one HSCI course.

HSCI 406-3 Global Perspectives in Indigenous Health

Examination of the health and health problems of Indigenous peoples from a global perspective. Comparative study of social and historical factors affecting Indigenous peoples that contribute to health conditions and health status. Efforts of Indigenous peoples to restore health to their Nations. Prerequisite: 60 units including one HSCI course.

HSCI 407-3 International Trade Agreements and Health Policy

A review of the impact of international trade agreements in shaping health policy in Canada as well as in other developed and developing countries. The impact of trade obligations in key health policy areas, including: the provision of health services, health insurance, intellectual property, pharmaceutical policy, bio-technology, the accreditation of health professionals and the ability of governments to regulate developments in the health care sector. Prerequisite: at least 60 units in health sciences including HSCI 130, 305 and at least one other upper division HSCI course.

HSCI 408-3 Plagues, Pollutants and Poverty: The Origins and Evolution of Public Health

Origins and evolution of public health. Transitions in public and population health, focusing on changing concepts and interventions in public health, such as the sanitarian movement, the rise of bacteriology and vaccines, nutritional deficiencies, chronic diseases, occupational health, maternal and child health, and environmental health. Prerequisite: HSCI majors with 90 units including HSCI 330.

HSCI 410-3 Exploratory Data Analysis

Regression and data analysis techniques for health research. Practical approaches to linear and logistic regression, multivariable modelling, interaction, variable selection, confounding, and measures of association. Computer-based laboratory exercises using statistical software applied to health datasets. Prerequisite: STAT 302. Recommended: HSCI 330.

HSCI 412-3 Health Communication

Theory and strategies for health communication in health systems and in particular cultural contexts. Interpersonal communication in health care, the relationship between belief and the construction of clinical realities, and communication for promoting public health. Social marketing and other strategies for health promotion targeting communities and persons of diverse cultural backgrounds. Communication about environmental and health risks. Prerequisite: HSCI 312 and two HSCI 200-level courses. Students who have taken HSCI 301 may not take this course for further credit.

HSCI 424-4 Strategic Applications of GIS in Health

The use of mapping strategies and geographic information systems in identifying disease patterns and health risks. The relation of health problems to the distribution of markers of exposure, susceptibility, and health impact, and resulting risk management strategies for intervention, mitigation, and disease prevention. Prerequisite: 60 units and two HSCI 200-level courses, or permission of instructor. Recommended: GEOG 255, CMPT 100.

HSCI 426-4 Immune System I: Basis of Innate and Adaptive Immunity

The basic organization of the immune system, including structure, function and genetics of antibodies, T-cell receptors, innate immune receptors, and the complement system. Innate, antibody and cellular immune responses and their control, and development of the cells involved in these responses. Prerequisite: MBB 331. HSCI 426 is identical to MBB 426 and HSCI 325 and students cannot take MBB 426 for further credit.

HSCI 427-3 Immune System II: Immune Responses in Health and Disease

The immunologic response to bacterial, viral and parasitic infections, immunological diseases, such as autoimmune diseases, immunodeficiency, hypersensitivity reactions (including asthma and allergy) and transplantation-rejection reactions. Immunotherapeutics and vaccine development. Prerequisite: HSCI 426 or MBB 426 or permission of the instructor. HSCI 427 is identical to MBB 427 and HSCI 425 and students cannot take HSCI 427 for further credit.

HSCI 431-3 The Global HIV/AIDS Epidemic

A multidisciplinary and international focus on the transmission, impact, prevention, and human aspects of the global HIV/AIDS epidemic. Prerequisite: 60 units including either HSCI 212 or 330.

HSCI 432-3 Infectious Disease Epidemiology

Tools for the surveillance, prevention, and control of infectious diseases and their application in public health programs. Prerequisite: HSCI 212, 330.

HSCI 439-3 Pathogenesis of Human and Animal Viral Infectious Diseases

Mechanisms underlying viral infectious diseases in humans and animals at the levels of the molecule, cell, organ and the individual. Virus spread in a host, host responses to the viral infection, and virus-host interactions that result in disease. Prerequisite: HSCI 338 - Animal virology and HSCI 321- Human pathophysiology.

HSCI 440-4 Cell Pathophysiology Laboratory

A review of pathophysiological mechanisms of disease with an emphasis on the molecular, cellular and genetic bases of pathology. Laboratory includes cell-biology experiments, histological preparations, and microscopic examination of normal and diseased tissues. Prerequisite: MBB 308 and HSCI 321, or permission from instructor.

HSCI 441-4 Virology Laboratory

Study, in a laboratory environment, of viruses as infectious agents that threaten human health and viral associated cancer as well as their use in gene therapy. Includes cell culture methods, virus isolation and quantification, virus purification, etc. Prerequisite: HSCI 338 - Animal Virology. One of - BISC 357- Gene Cloning, MBB 308. Molecular Biology laboratory, or MBB 309 - Biochemistry Laboratory

HSCI 442-4 Immunology Laboratory

Laboratory methods in immunology. Focus on the vertebrate immune system and the molecular and cellular principles underlying immune recognition. Experimental methods designed to combine serology, biochemistry, molecular biology, cell biology and genetics as a basis for understanding immunological aspects of health and disease. Prerequisite: HSCI or MBB 426, MBB 308.

HSCI 443-4 Molecular Toxicology Lab

The scientific principles underlying the toxic actions of various substances important to human health. The chemical nature of toxic substances, their mode of action, uptake and metabolism. Analytical techniques for analyzing samples of toxicological importance in the work and general environment and short-term assays used in risk assessment will be introduced. Prerequisite: HSCI 323, MBB 308.

HSCI 449-3 Community and Health Service

Multi-week service learning project with a community-based partner organization or school arranged each semester. Related class work addresses community partnerships, health promotion, reciprocity, local control, sustainability, participatory research, and skills. Prerequisite: 90 units including HSCI 312 and 319 or 327. Students with credit for HSCI 349 may not complete this course for credit

HSCI 450-3 Co-op Practicum III

Third term of work experience in the Health Sciences Co-operative Education Program. Units from this course do not count towards the units required for an 丁香园AV degree. Work terms are graded as Pass/Fail. Prerequisite: completion of HSCI 351 Co-op Practicum II.

HSCI 451-3 Co-op Practicum IV

Fourth term of work experience in the Health Sciences Co-operative Education Program. Units from this course do not count towards the units required for an 丁香园AV degree. Work terms are graded as Pass/Fail. Prerequisite: completion of HSCI 450 Co-op Practicum III.

HSCI 452-3 Co-op Practicum V

Fifth term of work experience in the Health Sciences Co-operative Education Program. Units from this course do not count towards the units required for an 丁香园AV degree. Work terms are graded as Pass/Fail. Prerequisite: completion of HSCI 451 Co-op Practicum IV.

HSCI 471-3 Special Topics in Health Sciences I

Selected topics in areas not currently offered within the undergraduate course offerings. Prerequisite: will vary according to topic.

HSCI 472-3 Special Topics in Health Sciences II

Selected topics in areas not currently offered within the undergraduate course offerings. Prerequisite: will vary according to topic.

HSCI 473-3 Special Topics in Health Sciences III

Selected topics in areas not currently offered within the undergraduate course offerings. Prerequisite: will vary according to topic.

HSCI 474-3 Seminar in Neuropharmacology

Mechanisms of drug action in the brain, including several classes of drugs and neurotransmitter systems that are involved in mental health disorders, drug addiction and neurodegeneration. Prerequisite: HSCI 323 and HSCI 321 or MBB 331.

HSCI 475-3 Seminar in Molecular Mechanisms of Epigenetics

Discussion of novel and advanced topics in chemical covalent modifications of chromatin that influence gene regulation. Prerequisite: MBB 331, or permission of the instructor.

HSCI 476-3 Seminar in Molecular Basis of Drug Action and Environmental Exposure

Current topics in molecular biology-based research into pathologies of disease related to drug and environmental exposures. Focus on systems pharmacology and the molecular determinants of drug and toxicant action as they relate to gene expression and signal transduction. Prerequisite: HSCI 323 and MBB 331, or permission of the instructor

HSCI 477-3 Seminar in Vaccine Immunology

Immunological concepts of vaccines and vaccinology including vaccination, correlates of immune protection, humoral and mucosal immunity, adjuvants, recombinant vaccine technology, 'designer' vaccines, and HIV/AIDS vaccine design as a paradigm for modern vaccinology. Prerequisite: BISC 303 and HSCI 426 or MBB 426, or permission of the instructor. Recommended: HSCI 427 or MBB 427.

HSCI 478-3 Seminar in Molecular Epidemiology of Infectious Diseases

Application of modern molecular methods to epidemiological questions. Globally-relevant and emerging infectious diseases will be highlighted. Prerequisite: HSCI 330 and MBB 331. Students with credit for HSCI 432 in 2010 may not complete HSCI 478 for further credit.

HSCI 479-3 Seminar in Aging-Related Neurodegenerative Disease

Molecular and cellular mechanisms underlying the pathogenesis of aging-related neurodegenerative diseases, and translational, bench-to-bedside, research topics related to therapeutic strategies and outcomes. Prerequisite: MBB 331 and HSCI 321.

HSCI 481-3 Senior Seminar in Social Health Science

An in-depth overview of the sociocultural, epidemiological, and policy aspects of population and public health. Prerequisite: HSCI majors with 90 units, including at least 15 upper division HSCI units. Other prerequisites may vary according to topic.

HSCI 482-3 Senior Seminar in Infectious Diseases

An in-depth overview of newly emerging and re-emerging infectious diseases in the context of disease prevention, surveillance and control. Prerequisite: HSCI 338 - Animal virology MBB/HSCI426 - Immune System issues of Innate and Adaptive Immunity.

HSCI 483-3 Senior Seminar in Environmental Health

An in-depth overview of environmental health, environmental risks and human activity in relation to environmental health in the context of disease prevention, surveillance and control. Prerequisite: HSCI majors with 90 units, including HSCI 304 and HSCI 330.

HSCI 484-3 Senior Seminar in Population Health Research

Scientific research in population health. Developing and evaluating research protocols, taking a general research question and turning it into an analysis plan, carrying out the analysis, and writing up the findings for presentation and publication. Prerequisite: HSCI majors with 90 units, including HSCI 330 and STAT 302, or permission from instructor.

HSCI 485-3 Senior Seminar in Mental Health and Addictions

Treatment of current issues in mental health and addictions from a population and public health perspective. Students will examine several topics from theoretical, methodological and policy perspectives. Prerequisite: HSCI majors with 90 units, including at least 15 upper division HSCI units. Other prerequisites may vary according to topic.

HSCI 486-3 Senior Seminar in Global Health

Treatment of current global health issues. Students will examine several topics from theoretical, methodological and policy perspectives. Prerequisite: HSCI majors with 90 units, including at least 15 upper division HSCI units. Other prerequisites may vary according to topic.

HSCI 488-3 Directed Studies in Health Sciences

Independent studies on topics selected in consultation with the supervising instructor. A student will be permitted to enroll in this course only if she or he obtains the prior written agreement of a professor who will act as research supervisor.

HSCI 489-3 Directed Research in Health Sciences

Independent research on topics selected in consultation with the supervising instructor. A student will be permitted to enrol in this course only if she or he obtains the prior written agreement of a professor who will act as research supervisor.

HSCI 490-3 Research Proposal

Research proposal for the honors thesis. HSCI 490, 491 and 492 together form the honors thesis. Limited to honors students upon written agreement of the faculty supervisor.

HSCI 491-3 Independent Research

Research for the honors thesis. HSCI 490, 491 and 492 together form the honors thesis. Limited to honors students upon written agreement of the faculty supervisor. Prerequisite/corequisite: HSCI 490. Students with credit for HSCI 493 or HSCI 494 may not take HSCI 491 for further credit.

HSCI 492-3 Honors Research Thesis

Independent honors research thesis. HSCI 490, 491 and 492 together form the honors thesis. Limited to honors students upon written agreement of the faculty supervisor. Prerequisite or corequisite: HSCI 491.

HSCI 493-6 Extended Independent Research

Independent research for the honors thesis. Three courses, HSCI 490-3, HSCI 492-3, and either 491-3, HSCI 493-6, or HSCI 494-9, together form the coursework for the honors thesis. This 6-credit option is for students who will devote about half time to their research during the semester. Limited to honors students upon written agreement of the faculty supervisor. Prerequisite: HSCI 490-3. Cannot get credit for HSCI 491-3 or HSCI 494.9.

HSCI 494-9 Independent Laboratory Research

Independent laboratory-based research for the honors thesis. Three courses, HSCI 490-3, HSCI 492-3, and either 491-3, HSCI 493-6, or HSCI 494-9, together form the coursework for the honors thesis. This 9-credit option is for students whose research requires close to full-time work in the laboratory during the semester. Limited to honors students upon written agreement of the faculty supervisor. Prerequisite: HSCI 490-3 Research Proposal. Cannot get credit for HSCI 491-3 or HSCI 493-6.

HSCI 499-3 Special Topics in Health Sciences III

A specific topic in health sciences which is not otherwise covered in depth in regular courses. Prerequisite/Corequisite: will vary according to topic.

HSCI 726-4 The Immune System I: Basis of Innate and Adaptive lmmunity

The basic organization of the immune system, including structure, function and genetics of antibodies, T-cell receptors, innate immune receptors, and the complement system. Innate, antibody and cellular immune responses and their control, and development of the cells involved in these responses. Prerequisite: MBB 331 or permission of the instructor. Students with credit for MBB or HSCI 426, MBB 826 or MBB 726 may not complete HSCI 726 for credit.

HSCI 727-3 Immune System II: Immune Responses in Health and Disease

The immunologic response to bacterial, viral and parasitic infections, immunological diseases, such as autoimmune diseases, immunodeficiency, hypersensitivity reactions (including asthma and allergy) and transplantation-rejection reactions. Immunotherapeutics and vaccine development. Prerequisite: MBB/HSCI 426 or permission of the instructor. Students with credit for MBB 427, HSCI 427 or MBB 727 may not complete HSCI 727 for credit.

HSCI 774-3 Seminar in Neuropharmacology

Mechanisms of drug action in the brain, including several classes of drugs and neurotransmitter systems that are involved in mental health disorders, drug addiction and neurodegeneration. Prerequisite: HSCI 323, MBB 331, or permission of the instructor.

HSCI 775-3 Seminar in Molecular Mechanisms of Epigenetics

Discussion of novel and advanced topics in chemical covalent modifications of chromatin that influence gene regulation. Prerequisite: MBB 331 or permission from the instructor.

HSCI 776-3 Seminar in Molecular Basis of Drug Action and Environmental Exposure

Topics in molecular biology-based research into pathologies of disease related to drug and environmental exposures will be discussed. Focus on systems pharmacology and the molecular determinants of drug and toxicant action as they relate to gene expression and signal transduction. Prerequisite: HSCI 323, MBB 331, or permission of the instructor.

HSCI 777-3 Seminar in Vaccine Immunology

Exposes current immunological concepts of vaccines and vaccinology including vaccination, correlates of immune protection, humoral and mucosal immunity, adjuvants, recombinant vaccine technology, 'designer' vaccines, and HIV/AIDS vaccine design as a paradigm for modern vaccinology. Current literature in these areas will be reviewed intensely. Prerequisite: BISC 303, MBB 426, or permission from the instructor.

HSCI 778-3 Seminar in Molecular Epidemiology of Infectious Diseases

Application of modern molecular methods to epidemiological questions. Globally-relevant and emerging infectious diseases will be highlighted. The course will emphasize critical review of the current literature in the field. Prerequisite: BISC 303, 330, MBB 331, or permission from the instructor.

HSCI 800-3 Fundamentals of Biostatistics

Introduction to the practice of statistics with examples from health sciences literatures. Emphasizes statistical thinking and basic statistical concepts. Coverage includes basic descriptive statistics, elementary probability concepts, probability and sampling models, exploratory data analysis for univariate and bivariate data, one sample and two sample tests for means and proportions. Prerequisite: admission to the graduate program or permission of the instructor. Students who have taken HSCI 800 Special Topics 'Introduction to Biostatistics' cannot take this course for credit.

HSCI 801-4 Biostatistics for Population Health Practice I

Basic statistical concepts as applied to diverse problems in epidemiologic and public health research. Emphasizes interpretation and concepts rather than calculations. Basic study designs' statistics. Descriptive and graphical methods, fundamentals of probability distribution, rates and standardization, contingency tables, odds ratios, confidence intervals, hypothesis testing, life tables, Linear regression. Prerequisite: an undergraduate course in statistics or completion of HSCI 800.

HSCI 802-4 Principles of Epidemiology for Public Health

The underlying concepts and methods of epidemiology in the context of population and public health. Study designs (clinical trials, cohort studies, case-control studies, and cross-sectional), measures of disease frequency and effect, validity and precision, confounding and effect modification, analysis of two-by-two tables, and options for control. Students will acquire skills in the critical interpretation of the epidemiologic literature, methodology of estimating measures of disease frequency and effect and common measures of potential impact; evaluation of study design; analysis of bias and confounding; and options for control of extraneous factors. HSCI 801 may be taken concurrently.

HSCI 803-4 Qualitative and Survey Research Methods

Methodologies and strategic research design for advances in knowledge and understanding in the health sciences. Problem definition, sampling, data collection, analysis, proposal writing, and ethical issues are addressed. Provides experiential and intellectual grounding in surveys, interviews, focus groups, and ethnography. Prerequisite: admission to the graduate program or permission of the instructor.

HSCI 804-3 Biostatistics for Population Health Practice II

Statistical methods related to public health. Probability distributions, basic statistical inference on means and proportions and general concepts of hypothesis testing. Measures of association. Simple and multivariable linear regression models, dummy variables, and logistic regression models. Survival data analysis. Prerequisite: HSCI 801.

HSCI 805-3 Intermediate Epidemiologic Methods

Follow-up course to HSCI 802. Designing, conducting, analyzing, and interpreting epidemiologic research. Theoretical frameworks, concepts of inference, measures of disease occurrence and effect, study designs, issues in measurement, bias, confounding, and interaction. Critical assessment of the epidemiologic and public health literature. Prerequisite: HSCI 801 and 802.

HSCI 806-3 Principles of Demographic Analysis

This seminar course is designed to introduce students to demographic techniques and principles through the discussion of the applications of various measures, case studies, and software programs. The emphasis is on applying techniques and principles learned in class to undertake demographic analyses in the lab. Prerequisite: HSCI 801.

HSCI 807-3 Researching Health Inequities

Critical examination of methodologies and methods for research on health inequities related to class, race, ethnicity, gender and other social axes of marginalization and power. Covers a range of disciplines (epidemiology, social sciences), methodologies (positivist, critical, feminist, indigenous) and methods (qualitative, quantitative, action-oriented). Emphasis on causes of and solutions to systemic health inequities. Prerequisite: HSCI 802, 803 and 838 or permission of instructor.

HSCI 815-3 Concepts of Population and Public Health Practice

Introduction to population health paradigms and the history of public health. Understanding the factors that influence health over the lifespan. Fundamentals of public health strategies including health promotion, public policy, disease prevention, communication in health, behavior change, and program planning and evaluation. Prerequisite: admission to the graduate program or permission of the Instructor.

HSCI 821-3 Introduction to Global Health

Problem-focused introduction to global health. Critical appraisal of current global health problems in the context of processes of globalization. Understanding and addressing health inequities, within and between countries. A case approach. Graded. Prerequisite: admission to the graduate program or permission of the instructor.

HSCI 822-3 Globalization and Health

The mechanisms by which globalization impacts health. Roles of technologies, politics, economics, legal structures, culture, and social environments. The positive and negative impacts of global trends in trade, ideology, governance, community building, conflict, poverty, and the environment. A case studies approach. Prerequisite: admission to the graduate program or permission of the instructor.

HSCI 823-3 Health, Gender and Development

Central role played by gender in health and development. Relationship of gender inequities to access to and control of resources needed to protect health. Use of gender lens in evaluating health systems and economic outcomes. Practical application of gender in health development approach to health financing, resource allocation policy problems in resource-constrained nations. A case studies approach. Prerequisite: admission to the graduate program or permission of the instructor.

HSCI 824-3 Comparative Health Care Systems

Concepts of health, illness, sickness and disease. History and development of health systems, and comparison of the social ethics, organization, and financing of different national health systems. The design of health systems - strengths and weaknesses of alternative systems for health care and delivery. Current strategies for health system reform in resource-rich and resource-constrained nations. A case studies approach. Prerequisite: admission to the graduate program or permission of the instructor.

HSCI 825-3 Advocacy and Communication

Health advocacy, the policy framework within which it operates, its key principles, skills, and practice issues. Role, theories, and methods of health communication and advocacy in global health from the community to global level. Useful means: media advocacy, community mobilization, and trans-national collaboration. Use of information technology to promote population health and pro-health policy change. A case studies approach. Prerequisite: admission to the graduate program or permission of the instructor.

HSCI 826-3 Program Planning and Evaluation

Practical approaches to health needs assessment, needs prioritization, health program planning, and health program evaluation in low-to-middle income countries and/or resource-poor settings. Gender-based analyses are emphasized throughout. A case study approach. Prerequisite: admission to the graduate program or permission of the instructor.

HSCI 827-3 Analysis of the Canadian Health Care Delivery System

Components of health care systems, issues, and interactions between components. System outputs, medical services and the delivery of primary health care. The Canadian health system and alternatives that impact it or provide better models for delivery. Effecting change, policy development, health system design; criteria for evaluating alternatives. Comparison of different measures of health status; trend analysis for predicting future health care and funding. Components of expenditure. Prerequisite: admission to the graduate program or permission of the instructor.

HSCI 829-3 Health Policy Making in a Global Context

A case-study based approach to policy analysis, formation, decision-making and evaluation in global health contexts. Frameworks for developing policy. Program planning and evaluation methodologies. Prerequisite: admission to the graduate program or permission of the instructor.

HSCI 830-3 Health Promotion

Population health promotion and disease prevention theories, frameworks, and techniques for planning, implementing and evaluating policy and programs in resource-constrained countries. Building collaborations and participatory community-based approaches. Addressing change at the individual, organizational, community, population, and global level. A case studies approach. Graded. Prerequisite: admission to the graduate program or permission of instructor.

HSCI 835-3 Social and Behavioural Contexts of Health and Disease

Examination of the major social and behavioral variables -- social class, poverty, income distribution, gender, race, social networks/support, psychological stress, community cohesion, and the work and neighborhood environment -- that affect the public's health. Evaluation of the empirical research linking each construct to population health status. Methods are introduced to operationalize each construct for the purposes of application in public health research. Prerequisite: admission to the graduate program or permission of the instructor.

HSCI 838-3 Theorizing Social Inequities and Health

Critical analysis of theories and frameworks central to research and practice on health inequities. Emphasis on mechanisms through which gender, race, ethnicity, social class and other social axes of marginalization and power intersect to influence health outcomes at the population level. Prerequisite: HSCI 835 or permission of instructor.

HSCI 839-3 Strategies for Reducing Health Inequities

Critical application of theory and research on social inequities and health to the development of interventions, programs and policies for reducing health inequities at the population level. Emphasis on critical, collaborative, evidence-based, reflexive public health practice. Prerequisite: HSCI 807, 838, or permission of the instructor.

HSCI 845-3 Environmental and Occupational Health

Globalization and industrialization impacts on the health of the environment, populations, and workers. Environmental hazards in consumables (food, air, and water) and waste (liquid, solid, and gaseous) with special reference to hazardous waste. Risk assessment in community, workplace, and residential settings. A case studies approach. Prerequisite: admission to the graduate program or permission of the instructor.

HSCI 846-3 Environmental Health Exposure Assessment and Analysis

Assessment and analysis of exposure to physical, chemical, and biological contaminants in environmental and occupational settings. Theory and methods of assessing exposure through direct and indirect methods. Introduction to statistical and modeling techniques used in interpreting exposure data, describing sources of exposure variability, and identifying important determinants of exposure. Prerequisite: HSCI 845 or permission of the instructor.

HSCI 847-3 Risk Assessment and Communication for Human Health

Concepts and tools involved in human health risk assessment, with a particular emphasis on those aspects relevant to occupational and environmental exposures. The main steps involved in a risk assessment and application to basic risk/exposure situations. Identify the strengths and weaknesses of different approaches. Risk management and the policy process. Prerequisite: HSCI 802 or permission of the instructor.

HSCI 849-3 Environmental and Occupational Epidemiology

Epidemiological studies of environmental and workplace exposures. Critical evaluation of epidemiological studies of environmental and occupational exposures. Prerequisite: HSCI 802, 845 or permission of the instructor.

HSCI 850-3 Air Pollution and Human Health

Basic air pollution concepts. Exploring the evidence of links between air pollution and adverse human health effects, including both mortality and morbidity. Air quality management at the international, national, and local levels. Focus includes airborne particles, traffic-generated pollution and indoor biomass burning. Prerequisite: HSCI 845 or permission of the instructor.

HSCI 851-3 Workplace Health and Safety Management

Workplace hazards will be examined in a cross section of industries, including their associated disabilities and costs, both to workers and the broader society and economy. Students will gain basic scientific knowledge required to identify and analyze the most prevalent occupational health and safety hazards, and will be able to evaluate and design safer workplaces. Prerequisite: admission to the graduate program or permission of the instructor.

HSCI 855-3 Disease Prevention and Control

Infectious and chronic disease prevention and control strategies and program implementation. Components of disease prevention and control programs, including surveillance, epidemic preparedness, immunization, outbreak response. How they apply to specific diseases. A global perspective, including low and middle income countries. Case studies. Prerequisite: admission to the graduate program or permission of the instructor.

HSCI 865-1 Colloquium in Immunology and Infectious Diseases

Student presentations from the primary literature and from students' original research. Prerequisite: admission to the graduate program or permission of the instructor.

HSCI 866-3 Host-Microbe Interactions

Infectious pathogens (viruses, bacteria, fungi, protozoa, helminths), their life cycle including vectors of transmission, the biological mechanisms by which they establish infection and cause disease. Pathogenic and protective aspects of the human response to infection; roles of vaccines and chemotherapy. Impact of environmental, ecological and social/behavioral factors on the host-pathogen relationship. Prerequisite: admission to the graduate program or permission of the instructor.

HSCI 868-3 Globalization and Infectious Diseases

Identifying a range of alternatives as most appropriate and feasible for controlling infectious diseases, and solutions to increase the infectious diseases prevention and treatment agenda in public health, clinical policy and practice at a global level. Prerequisite: admission to the graduate program, or permission of the instructor.

HSCI 870-3 Global Health and International Affairs

Intersection of international affairs and global health. Pressing global health issues are analyzed as they intersect with the global economy, international development, and security. Prerequisite: 丁香园AV to the graduate program, or permission of the instructor.

HSCI 880-3 Practicum

Students participate in a workplace practicum to obtain experience in community public health practices. Practica are the equivalent of full-time course work, and may focus on local, regional, national or international health practices. Following completion of the practicum, students are expected to be on campus to prepare a poster presentation summarizing their practicum experience. Graded complete or incomplete. Prerequisite: students will consult with their senior supervisor on all courses that must be taken before going on practicum. All students are expected to complete at minimum the following courses: HSCI 801, 802, 803, 901. Under special circumstances students may request written permission from the director, public health practice, and the senior supervisor to substitute one of the prerequisite courses, or to carry out the practicum prior to completion of the required courses.

HSCI 886-6 MSc Thesis Proposal

Development and presentation of proposal for MSc thesis research. Prerequisite: enrolment in HSCI MSc program.

HSCI 887-12 MSc Thesis

HSCI 889-3 Special Topics in Infectious Diseases

Explores topics, current and emerging, in infectious diseases. Prerequisite: admission to the graduate program, or permission of the instructor.

HSCI 890-4 Special Topics in Health Sciences

Special topics in areas not currently covered within the graduate program offerings. Prerequisites: depending on the special topic offered.

HSCI 891-3 Special Topics in Health Sciences

Special topics in areas not currently covered within the graduate program offerings. Prerequisite will depend on the special topic offered.

HSCI 892-2 Special Topics in Health Sciences

Special topics in areas not currently covered within the graduate program offerings. Prerequisite will depend on the special topic offered.

HSCI 893-3 Directed Studies in Health Sciences

HSCI 894-4 Directed Studies in Health Sciences

HSCI 895-0 Project Completion

Master's Project in progress. Prerequisite: HSCI 897-3.

HSCI 896-0 Thesis Completion

Master's Thesis in progress. Registration in this course is equivalent to full time course work. Prerequisite: HSCI 898.

HSCI 897-3 Master's Project

Graded incomplete/complete. Prerequisite: HSCI 880.

HSCI 898-6 Master's Thesis

Graded incomplete/complete.

HSCI 900-0 FHS Research Seminars

Weekly seminars will consist of presentations by faculty, visiting scholars and students followed by discussion. Required course for all graduate students in health sciences. Offered spring and fall terms. Graded satisfactory/unsatisfactory.

HSCI 901-1 Preparation for Public Health Practice

Seminars, workshops and lectures designed to develop skills for public health practice. Includes the practicum planning process. Normally students complete this course in the fall and spring term of their first year. It must be completed prior to the practicum. Prerequisite: admission to the graduate program or permission of the instructor.

HSCI 902-3 Interdisciplinary Seminar in the Health Sciences

Epistemological and philosophical groundings for research inquiry and the ways in which different approaches manifest themselves in developing research questions and choosing methods for research in health sciences. Issues related to measurement, inference, experimental and quasi-experimental research designs, interpretive and ethnographic methods of data collection will be examined. Prerequisite: 丁香园AV to the MSc program, or the MPH (thesis) program, or the PhD program in the Faculty of Health Sciences, or consent of the instructor.

HSCI 902-3 Interdisciplinary Seminar in the Health Sciences

Epistemological and philosophical groundings for research inquiry and the ways in which different approaches manifest themselves in developing research questions and choosing methods for research in health sciences. Issues related to measurement, inference, experimental and quasi-experimental research designs, interpretive and ethnographic methods of data collection will be examined. Prerequisite: 丁香园AV to the MSc program, or the MPH (thesis) program, or the PhD program in the Faculty of Health Sciences, or consent of the instructor.

HSCI 903-1 Interdisciplinary Research Colloquium 1

Recent research articles, book chapters, or students' research from a range of health sciences disciplines will be presented and discussed, with an emphasis on critical analysis. Prerequisite: 丁香园AV to the MPH (thesis) program, or the MSc program, or the PhD program in the Faculty of Health Sciences, or consent of the instructor.

HSCI 904-1 Interdisciplinary Research Colloquium 2

Recent research articles, book chapters, or students' research from a range of health sciences disciplines will be presented and discussed, with an emphasis on critical analysis. Prerequisite: 丁香园AV to the MPH (thesis) program, or the MSC program, or the PhD program in the Faculty of Health Sciences, or permission of the instructor.

HSCI 905-1 Interdisciplinary Research Colloquium 3

Recent research articles, book chapters, or students' research from a range of health sciences disciplines will be presented and discussed with an emphasis on critical analysis. Prerequisite: 丁香园AV to the MPH (thesis) program, or the MSc program, or the PhD program in the Faculty of Health Sciences, or permission of the instructor.

HSCI 983-6 Comprehensive Exam and Thesis Proposal

Comprehensive examination and thesis proposal preparation.

HSCI 990-6 Thesis Research

Doctoral thesis research.

HSCI 998-6 Thesis Preparation and Defence

Preparation and defence of the doctoral thesis.

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