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An introduction to the biochemical and physiological mechanisms of living organisms. Topics covered include cell structure and function, DNA replication and the flow of genetic information, enzyme function, metabolism and physiology of microorganisms, plants, and animals. Prerequisite: High school Biology 12 (or equivalent) with a C grade or better, or BISC 100 with C- or better, or BISC 113 with C+ or better, or HSCI 100 with C+ or better; and High school Chemistry 12 (or equivalent) with a C grade or better, or CHEM 111 with a C- or better. Breadth-Science.

Survey of the diversity of life, and its evolutionary history on earth. The student is introduced to the study of genetics, development, and evolution, giving an overview of how these processes interact to produce form and function. Also included are principles of behavior and ecological relationships of organisms to each other and their environment. Prerequisite: High school biology 12 (or equivalent) with a C grade or better, or BISC 100 with C- or better, or BISC 113 with C+ or better, or HSCI 100 with C+ or better. Breadth-Science.

Principles and concepts of the transmission of genetic information. Prerequisite: BISC 101 and 102 with a grade of C- or better.

Survey of theories and laboratory procedures for assessing human health status and physical performance, including biomechanics, body composition, development, environmental physiology, ergonomics, exercise physiology and motor learning. Functional anatomy and physiology of the cardiovascular, nervous, respiratory, skeletal and skeletal muscle systems in relation to physical activity are explored. Prerequisite: One of Grade 12 Anatomy and Physiology, Biology, Chemistry or Physics with a grade of C or better; or one of BPK 105, BPK 110, BPK 143, BISC 100, BISC 113 or HSCI 100 with a grade of C or better. Breadth-Science.

This course will cover the application of basic mechanics to human movement. It will provide students with a basic understanding of how forces act on body segments and how movements are produced. The subject matter of this course is relevant to quantifying all forms of physical activity, from activities of daily living, physically challenged movement patterns, to elite athletic performance. It also has applications in medical settings, including rehabilitation and sports medicine. Prerequisite: MATH 150, 151 or 154, MATH 152 or 155 (may be taken concurrently), PHYS 101 (or 120 or 125 or 140), BPK 142. Quantitative.

An introductory survey of human physiology with an emphasis on mechanisms of regulation and integration. Anatomy of structures will be detailed only when it is critical to a functional understanding. Although this is intended as a survey course, some topics will be covered in reasonable detail in order to give insight into mechanisms of function. Prerequisite: BISC 101, CHEM 281, PHYS 101 and 102. BPK 208 may not be used as a substitute for BPK 205 by students in the BPK Major and Honours programs. BPK Major and Honours students who have taken BPK 105 must also take BPK 205. For students taking both of these courses, credit will only be given for BPK 205.

Students are introduced to basic concepts in the sensorimotor planning and control of movement. Topics include the factors and disorders affecting movement, sensory and motor physiology, sensorimotor integration, current theories of motor control, and motor learning. Taught from a behavioral and neurophysiological perspective that explores psychological influences on motor control. Prerequisite: BPK 142 or permission of instructor.

Atomic and molecular structure; chemical bonding; thermochemistry; elements; periodic table; gases liquids, solids, and solutions. This course includes a laboratory component. Prerequisite: Chemistry 12 with a minimum grade of C, or CHEM 109 or 111 with a minimum grade of C-. Students with credit for CHEM 120 or 125 may not take this course for further credit. Quantitative/Breadth-Science.

Chemical equilibria; electrochemistry; chemical thermodynamics; kinetics. Students who intend to take further laboratory courses in chemistry should take CHEM 122 concurrently with CHEM 126. Prerequisite: CHEM 120 or 121 with a minimum grade of C-. Students with credit for CHEM 124 or CHEM 180 may not take this course for further credit. Quantitative.

Experiments in chemical equilibrium, acids and bases, qualitative analysis, electrochemistry and chemical kinetics. Prerequisite: CHEM 121 with a minimum grade of C-. Corequisite: CHEM 122. Quantitative.

Structure, bonding, physical and chemical properties of simple organic compounds. Introduction to spectroscopy. Kinetics and mechanisms of organic reactions. This course includes a laboratory component. Prerequisite: CHEM 121 with a minimum grade of C-. Corequisite: CHEM 122. Students with credit for CHEM 280 or CHEM 285 may not take this course for further credit. Quantitative.

The structure, function and synthesis of proteins, RNA and DNA and their interrelated biological functions within the cell. An introduction to molecular biology techniques and methods of protein purification and analysis. Prerequisite: or Corequisite CHEM 281.

A study of the molecular processes which underlie cell structure and function, integrating ultrastructural, physiological and biochemical approaches. Modern techniques used in the analysis of organelle and cell function are integral parts of the course. Prerequisite: MBB 222, BISC 101, CHEM 281 with grades of C- or better. Corequisite or Prerequisite: CHEM 282 or CHEM 283.

Research methodology and associated statistical analysis techniques for students with training in the life sciences. Intended to be particularly accessible to students who are not specializing in Statistics. Prerequisite: Recommended: 30 units. Students cannot obtain credit for STAT 201 if they already have credit for - or are taking concurrently - STAT 101, 203, 205, 285, or any upper division STAT course. Quantitative.

Polyfunctional organic compounds and complex organic reactions. Introduction to natural products. Prerequisite: CHEM 281 with a minimum grade of C-. Students with credit for CHEM 283 may not take this course for further credit. Quantitative.

An advanced treatment of Organic Chemistry II. Topics include dienes and their reactivity, conjugation and aromaticity, aromatic substitution reactions, carboxylic acids and their derivatives, ketones and aldehydes, biological molecules, radical reactions, organometallic reagents, pericyclic reactions and planning multi-step synthesis. Prerequisite: CHEM 281 with a minimum grade of C-. Students with credit for CHEM 282 may not take this course for further credit. Quantitative.

Designed for students specializing in mathematics, physics, chemistry, computing science and engineering. Topics as for Math 151 with a more extensive review of functions, their properties and their graphs. Recommended for students with no previous knowledge of Calculus. In addition to regularly scheduled lectures, students enrolled in this course are encouraged to come for assistance to the Calculus Workshop (Burnaby), or Math Open Lab (Surrey). Prerequisite: Pre-Calculus 12 (or equivalent) with a grade of at least B+, or MATH 100 with a grade of at least B-, or achieving a satisfactory grade on the ¶¡ÏãÔ°AV Calculus Readiness Test. Students with credit for either MATH 151, 154 or 157 may not take MATH 150 for further credit. Quantitative.

Designed for students specializing in mathematics, physics, chemistry, computing science and engineering. Logarithmic and exponential functions, trigonometric functions, inverse functions. Limits, continuity, and derivatives. Techniques of differentiation, including logarithmic and implicit differentiation. The Mean Value Theorem. Applications of differentiation including extrema, curve sketching, Newton's method. Introduction to modeling with differential equations. Polar coordinates, parametric curves. Prerequisite: Pre-Calculus 12 (or equivalent) with a grade of at least A, or MATH 100 with a grade of at least B, or achieving a satisfactory grade on the ¶¡ÏãÔ°AV Calculus Readiness Test. Students with credit for either MATH 150, 154 or 157 may not take MATH 151 for further credit. Quantitative.

Designed for students specializing in the life sciences. Topics include: limits, growth rate and the derivative; elementary functions, optimization and approximation methods, and their applications, integration, and differential equations; mathematical models of biological processes and their implementation and analysis using software. Prerequisite: Pre-Calculus 12 (or equivalent) with a grade of at least B, or MATH 100 with a grade of at least C-, or achieving a satisfactory grade on the ¶¡ÏãÔ°AV Calculus Readiness Test. Students with credit for either MATH 150, 151 or 157 may not take MATH 154 for further credit. Quantitative.

Riemann sum, Fundamental Theorem of Calculus, definite, indefinite and improper integrals, approximate integration, integration techniques, applications of integration. First-order separable differential equations and growth models. Sequences and series, series tests, power series, convergence and applications of power series. Prerequisite: MATH 150 or 151, with a minimum grade of C-; or MATH 154 or 157 with a grade of at least B. Students with credit for MATH 155 or 158 may not take this course for further credit. Quantitative.

Designed for students specializing in the life sciences. Topics include: vectors and matrices, partial derivatives, multi-dimensional integrals, systems of differential equations, compartment models, graphs and networks, and their applications to the life sciences; mathematical models of multi-component biological processes and their implementation and analysis using software. Prerequisite: MATH 150, 151 or 154, with a minimum grade of C-; or MATH 157 with a grade of at least B. Students with credit for MATH 152 or 158 may not take this course for further credit. Quantitative.

Force and motion, conservation of energy and momentum, fluids, properties of soft matter and thermal physics with applications taken from the life sciences. Prerequisite: BC Principles of Physics 12 or PHYS 100 or equivalent, with a minimum grade of C-. This prerequisite may be waived, at the discretion of the department, as determined by the student's performance on a regularly scheduled PHYS 100 final exam. Please consult the physics advisor for further details. Corequisite: MATH 150 or 151 or 154 or 157; BISC 100 or 101 or 102. Recommended Corequisite: PHYS 132. Students with credit for PHYS 120, 125 or 140 may not take this course for further credit. Quantitative/Breadth-Science.

A general calculus-based introduction to mechanics. Topics include translational and rotational motion, momentum, energy, gravitation, and selected topics in modern physics. Prerequisite: BC Principles of Physics 12 or PHYS 100 or equivalent, with a minimum grade of C-. This prerequisite may be waived, at the discretion of the department, as determined by the student's performance on a regularly scheduled PHYS 100 final exam. Please consult the physics advisor for further details. Corequisite: MATH 150 or 151 or 154. Recommended Corequisite: PHYS 132. Students with credit for PHYS 101, 125 or 140 may not take this course for further credit. Quantitative/Breadth-Science.

An enriched course in mechanics for students with good preparation in physics and mathematics. Special relativity and classical topics such as translational and rotational dynamics and conservation laws will be given a much more sophisticated treatment than in our other first-year courses. Prerequisite: Permission of the department. Corequisite: MATH 151. Recommended Corequisite: PHYS 132. Students with credit for PHYS 101, 120 or PHYS 140 may not take PHYS 125 for further credit. Quantitative.

A general calculus-based introduction to mechanics taught in an integrated lecture-laboratory environment. Topics include translational and rotational motion, momentum, energy, gravitation, and selected topics in modern physics. Prerequisite: BC Principles of Physics 12, or PHYS 100 or equivalent, with a minimum grade of C-. Corequisite: MATH 150 or 151 or 154. Students with credit for PHYS 125 or 120 or 101 may not take this course for further credit. Quantitative/Breadth-Science.

Waves and optics; electricity and magnetism; modern physics emphasizing radioactivity, with applications taken from the life sciences. Prerequisite: PHYS 101 or 120 or 125 or 140; MATH 150 or 151 or 154 or 157; both with a minimum grade of C-. Corequisite: BISC 100 or 101 or 102. Recommended Corequisites: MATH 152, 155 or 158; PHYS 133. Students with credit for PHYS 121, 126, or 141 may not take this course for further credit. Quantitative/Breadth-Science.

A general calculus-based introduction to electricity, magnetism and optics. Topics include electricity, magnetism, simple circuits, optics and topics from applied physics. Prerequisite: PHYS 120 or 125 or 140, with a minimum grade of C-, or PHYS 101 with a minimum grade of B. Corequisite: MATH 152 or 155. Recommended Corequisite: PHYS 133. Students with credit for PHYS 102, 126 or 141 may not take this course for further credit. Quantitative/Breadth-Science.

An enriched course in electromagnetism for students with good preparation in physics and mathematics. Classical topics such as waves, electricity and magnetism, as well as wave particle duality and the birth of Quantum Mechanics, will be given a much more sophisticated treatment than in our other first year courses. Prerequisite: PHYS 125 with a minimum grade of C- or permission of the department. Corequisite: MATH 152. Recommended Corequisite: PHYS 133. Students with credit in PHYS 102, 121 or 141 may not take this course for further credit. Quantitative.

A general calculus-based introduction to electricity, magnetism and optics taught in an integrated lecture-laboratory environment. Topics include electricity, magnetism, simple circuits, optics and topics from applied physics. Prerequisite: PHYS 120 or PHYS 125 or PHYS 140, with a minimum grade of C-, or PHYS 101 with a minimum grade of B. Corequisite: MATH 152 or MATH 155. Students with credit for PHYS 126 or 121 or 102 may not take this course for further credit. Quantitative/Breadth-Science.

Covers research design, measurement, data analysis, and hypothesis testing, as well as techniques for data acquisition, signal processing, and modeling relevant to research in Biomedical Physiology and Kinesiology. There is also a focus on scientific writing, with opportunities for feedback and revision. Prerequisite: BPK 142, STAT 201 and two of BPK 201, 205 and 207. Students with credit for BPK 304 may not repeat this course for further credit. Writing/Quantitative.

A detailed examination of the physiology and pathophysiology of the cardiac, vascular and respiratory systems. The course focuses on integration of physiological mechanisms at the molecular, cellular and systems levels. Prerequisite: BPK 205, MBB 231 (or 201), MATH 155 (or 152). Majors from outside BPK require BPK 205 (or BISC 305), MBB 231 (or 201), MATH 155 (or 152) plus permission of the instructor.

A detailed examination of the physiology and pathophysiology of the nervous system, skeletal muscle and connective tissue. The course focuses on integration of physiological mechanisms at the molecular, cellular and systems levels. Prerequisite: BPK 207. Corequisite: BPK 305. Majors from outside BPK require BPK 205 (or BISC 305), MBB 231 (or 201), MATH 155 (or 152) plus permission of the instructor.

A detailed examination of the physiology and pathophysiology of the gastrointestinal, renal, endocrine, immune and reproductive systems. The course focuses on integration of physiological mechanisms at the molecular, cellular and systems levels. Prerequisite: BPK 305. Corequisite: BPK 306; however, students who took BPK 306 prior to Fall 2017, cannot take this course. Majors from outside BPK require BPK 205 (or BISC 305), MBB 231 (or 201), MATH 155 or 152 plus permission of the instructor.

A detailed study of human anatomy with emphasis on clinically relevant applications in health, injury and disease. Virtual cadaver dissection, comparative laboratory work, and an introduction to medical imaging emphasize the layered, three-dimensional organization of the human body. Participation in all labs is required. Prerequisite: ¶¡ÏãÔ°AV to the major or honours program in Behavioural Neuroscience or Biomedical Physiology or Kinesiology. BPK 142, 201, 205 and at least 60 units. Behavioral Neuroscience Major and Honours students require BPK 142, 205, PSYC 280 and at least 60 units. BPK major and honours students who have taken BPK 325 must also take BPK 326. For students taking both of these courses, credit will only be given for BPK 326.

Experiments dealing with the nervous, muscular, cardiovascular, respiratory, and renal systems are covered. Prerequisite: BPK 305 and 306. Quantitative.

An advanced laboratory course in cellular physiological techniques providing students with theoretical and practical training in cellular physiology laboratory techniques such as DNA and RNA manipulation and quantification, immunofluorescence imaging of protein expression, tissue contraction studies and recording of nerve action potentials and modulation. Prerequisite: STAT 201 and BPK 305 for BPK majors or STAT 201 and one of BISC 305, 405, or 455 with a C- or better for BISC majors. Enrollment of non-BPK and non-BISC majors require permission of the instructor. Writing.

Only students in the honours program may enroll in BPK 491. Prerequisite: 90 units, BPK 304W (may be taken concurrently) and permission of the chair of the undergraduate program committee. A minimum grade of B in this course is needed to register in BPK 495 or BPK 499. Students with credit for BPK 497 may not take this course for further credit.

Student will perform an individual research project under the guidance and supervision of a faculty member. The project will carry out the research for the honours thesis proposed in BPK 491 - Undergraduate Honours Thesis Proposal. Prerequisite: BPK 491 (minimum grade of B). Corequisite: BPK 499. Only students in the honours program may enroll in BPK 495. Students with credit for BPK 499 prior to Fall 2016 may not take this course for further credit.

A written thesis based on research previously proposed in BPK 491 and performed in BPK 495. Regulations regarding the locale of the work, supervision and other arrangements, follow those for BPK 491. The written thesis should be submitted to the chair of the undergraduate program committee by the last day of exams of the term. The thesis will also be presented orally as a seminar in an open forum at the end of the term. Students may enroll in a maximum of one additional course concurrently with BPK 499 and BPK 495 with permission from the faculty honours supervisor. Prerequisite: BPK 491 (minimum grade of B). Corequisite: BPK 495. Only students in the honours program may enroll in BPK 499.

The enzymes and intermediates of major catabolic and anabolic pathways. Their regulation and integration in health and disease states. Prerequisite: MBB 231, with a minimum grade of C.

The phenomenon of organic evolution, and the major forces leading to changes in allele frequencies over time, i.e. natural selection and genetic drift. Topics include adaptation, speciation, the origin of life, and the major evolutionary trends over geological time. Prerequisite: BISC 202 with a grade of C- or better. Recommended: BISC 204. Students with credit for BISC 400 may not take this course for further credit.

Discussion and manipulations of some of the organisms and techniques applicable to genetic analysis. Students are required to come into the lab on average of two hours per week in addition to the four hour scheduled lab each week for project work. Prerequisite: BISC 202 with a grade of C- or better. Students with credit for BISC 302 may not take this course for further credit. Writing.

The biology of micro-organisms and their significance in the understanding of cellular processes. Students are required to come into the lab on average of two hours per week in addition to the four hour scheduled lab each week for project work. Prerequisite: BISC 102 and MBB 231 with a grade of C- or better.

A review of the evolution and the taxonomy of the vertebrate classes. A comparative study of their organ systems and functions with particular reference to reproduction. A comparison of the functional morphology of some species by laboratory dissections. Prerequisite: BISC 101 and 102 with a grade of C- or better.

Classical and modern experimental approaches will be described for understanding development of embryos of several species having common and distinctive features. These approaches are at the organismal, cellular, molecular and genetic levels. Prerequisite: BISC 202, MBB 222, MBB 231 with a grade of C- or better.

Techniques in gene cloning and the evaluation of gene function are introduced in lectures and practiced in labs. Lab exercises include genomic DNA, RNA, and plasmid purification; PCR; various cloning techniques; and construction of novel genes. Students are introduced to additional techniques in lectures including gene editing, and genome sequencing. Prerequisite: BISC 202, MBB 222, and MBB 231, all with a grade of C- or better. Recommended: MBB 331. Students with credit for MBB 308 may not take this course for further credit.

The lectures will explore two or three major themes in current cell biology, such as cell motility, the cell cycle, and cellular signalling. A critical component of the course is to develop an understanding of the experimental basis of our knowledge about cells. Prerequisite: MBB 222, 231 with C- or better, and completion of 75 units, or completion of BISC 305 or 366 with a C- or better. Students with credit for BISC 372 under this topic may not take this course for further credit.

Neuroscience, focusing on physiological, cellular and molecular mechanisms. Topics include: cellular and subcellular organization of the nervous system, electrical properties of neurons, ion channels, synaptic transmission, sensory systems, learning and memory, neurodegenerative diseases. Prerequisite: BISC 205 or BPK 205 and MBB 231 with a grade of C- or better. Students who have completed BISC 472 under the title 'Neurobiology' may not complete BISC 405 for further credit.

Students are introduced to models and simulations for biological systems at the ecosystem, organismal, cellular, and molecular levels. They will discover how to design and use models, and will then apply these skills to build their own model using basic mathematical tools, Excel, and Matlab. Prerequisite: MATH 150 or 151, and 152 both with a grade of C+ or better, or MATH 154 and 155 both with a grade of B or better; and at least 60 units; or permission of the instructor. Recommended: A 100-level biology course. Students who have taken Special Topics course BISC 475 "Movement, Molecules, and Models" may not take BISC 421 for further credit. Quantitative.

All aspects of neuronal development from the specification of neurons in the early embryo to the formation and maturation of neuronal circuits. Both invertebrate and vertebrate model organisms will be studied with emphasis on the molecular basis of nervous system development. Prerequisite: BISC 101, BISC 102, BISC 202, MBB 222, MBB 231; all with a grade of C- or better. Recommended: BISC 333 or MBB 331. Students with credit for MBB 444 may not take this course for further credit. Students who have taken Special Topics BISC 472 or BISC 474 Nervous System Development may not take this course for further credit.

The course provides an overview of "omics" methods in large-scale identification of gene functions in various organisms, and demonstrates how this knowledge can be applied in genomics fields, including plant and animal breeding. Prerequisite: BISC 101, BISC 102, BISC 202, MBB 222, MBB 231, and either BISC 357 or MBB 331; all with a grade of C- or better. Students who have taken Special Topics BISC 471 Applied Genomics may not take this course for further credit.

This course provides students with an advanced, detailed understanding of a variety of cell biological topics with particular attention given to the cytoskeleton, intercellular junctions, vesicle trafficking and post-translational modifications of proteins associated with those topics. Students will also be exposed to the history of cell biology throughout the course. Prerequisite: BISC 101, BISC 102, MBB 222 and MBB 231, all with a minimum grade of C-. Students who have completed BISC 472 under the title "Advanced Cell Biology" may not take this course for further credit.

Elements of physical chemistry from the macroscopic point of view. Thermodynamics, and its applications to chemical equilibrium. Chemical kinetics and reaction rate theories. Prerequisite: CHEM 260 with a minimum grade of C-. Recommended: MATH 251. MBB 323 will be accepted in lieu of CHEM 360. Quantitative.

Modern molecular biological and recombinant nucleic acid methods will be covered. Examples are DNA and RNA isolation, plasmid preparation, restriction enzyme digestion, DNA cloning and polymerase chain reaction. Prerequisite: or corequisite: MBB 331 with a minimum grade of C-. Students with credit for BISC 357 may not take this course for further credit.

Contemporary techniques in biochemistry including protein purification, immunochemical methods, and lipid characterization. Prerequisite: MBB 231, with a minimum grade of C. Recommended: CHEM 215 and CHEM 286 precede MBB 309W. Writing.

Biochemical and molecular aspects of cellular function, interactions and communication including cell cycle, apoptosis, cancer, neuronal transmission and the signal transduction pathways that integrate them. Prerequisite: MBB 231, with a minimum grade of C.

Introduction to physical biochemistry including thermodynamics, spectroscopic principles and applications, and molecular transport and interactions. The physical properties and structure determination of biomolecules will be emphasized. Prerequisite: MATH 152 (or 155), PHYS 121 (or 102, or 126, or 141), CHEM 122 (or 102), MBB 222 with a minimum grade of C.

An exploration of the fundamental aspects of proteins; their chemical and physical nature, their synthesis, stability and turnover, as well as their structure and function. Methods of protein analysis and structure determination will be presented. Prerequisite: MBB 222 with a minimum grade of C.

The study of DNA and RNA in relation to gene structure and expression: DNA replication and the regulation of gene expression in bacteria and higher organisms. Introduction to recombinant DNA and cloning theory; natural vector structures and recombinant vector construction. Prerequisite: MBB 231, and BISC 202, with a minimum grade of C.

Major topics in genomics and bioinformatics, with integrated discussion of associated ethical/legal/social issues. An overview of laboratory and computer-based methods to study genomes, and their applications. Hands-on computer lab session providing an opportunity to use and experiment with bioinformatics software and databases utilized in genomics and bioinformatics research. Prerequisite: MBB 231, BISC 202 and either MBB 243 or 3 units of CMPT or equivalent, all with a minimum grade of C. Recommended: STAT 201 (or an equivalent statistics course) or STAT 270.

A physics perspective on cellular structure and composition; random walks and diffusion; properties of fluids, cell motion; entropy and the properties of soft materials; structure and function of proteins; signal propagation in nerves. Prerequisite: Completion of 45 units including CHEM 122; MATH 152 or MATH 155; PHYS 102 or PHYS 121 or PHYS 126 or PHYS 141; all with a minimum grade of C-. Recommended: BISC 101. Quantitative.

A laboratory course on the quantitative biomechanical evaluation of human movement. Students will learn analysis techniques for quantifying kinematics and kinetics of body segments in athletes, normal populations, and special populations during activities such as walking and jumping. Experiments will look at the nature of muscular force generation, and the mechanical impedance properties of the musculoskeletal system, as well as patterns of muscle activation, using surface EMG. Prerequisite: PHYS 102 (or 121 or 126 or 141), BPK 201. Quantitative.

The study of human physiological responses and adaptations to acute and chronic exercise/work. Cardiorespiratory, cellular and metabolic adaptations will be studied and discussed in detail. Prerequisite: BPK 205, MBB 201 (or 231). Recommended: BPK 201.

Light and electron microscopic study of mammalian tissues and organs with emphasis on human systems. Prerequisite: One of BPK 325, 326, BISC 305, 316.

Relationships among health, physical activity, and other health-associated behaviors are examined. In addition, the theories and models of health behavior, in the context of intervention and promotion strategies, are discussed. Pertinent background information is provided, concerning the influence of fitness on various disease states, as well as the epidemiology of health and exercise behaviors. Prerequisite: BPK 142, STAT 201 (or PSYC 201). Recommended: BPK 140.

The mechanics and function of skeletal muscle, from the level of single muscle fibres to the whole muscle-tendon unit. The role of muscle structure, recruitment patterns and contractile conditions to the force development, power output and efficiency of contractions will be considered. Theoretical, experimental and computational aspects will be covered. Prerequisite: 90 credits, BPK 201 and 205, or BPK 208. Students with credit for BPK 421, Muscle Biomechanics, may not take this course for further credit.

Extension of BPK 201 provides students with an understanding of structure-function relations in musculoskeletal tissues (bone, cartilage and muscle) in health and disease. Includes effect of disease and aging on physiological and biomechanical properties, mechanics and prevention of tissue injury, and design of implants and prostheses. Prerequisite: BPK 201 and BPK 306.

Wearable technology hardware will be provided for use at home to measure, analyze and understand your own physiology, including aspects of your muscular and cardiovascular systems. In remote labs, you will use computer programming to implement industry-standard algorithms to analyze and understand the physiological measurements. Prerequisite: BPK 305 and 306.

Examines advanced and current topics in vascular physiology, with a focus on cell structure and signal transduction pathways related angiogenesis, hypertension, diabetes and obesity. Current research methodology and the relevance of vascular physiology to human health will be considered. Tutorial sessions apply course concepts through problem-based learning and literature analysis. Prerequisite: BPK 305. Students who have taken BPK 420 Advanced Topics in Vascular Physiology may not take this course for further credit.

A detailed analysis of the molecular and cellular basis of cardiac function employing a multidisciplinary approach including structure (histology, ultrastructure, molecular), biophysics (electrophysiology and molecular/cellular biomechanics), physiology, biochemistry and cellular/molecular biology. Discussion of experimental techniques, including human induced pluripotent stem-derived cardiomyocytes (hiPSC-CMs), will be used to examine the mechanisms by which inherited arrhythmias and cardiomyopathies manifest as a pathological phenotype. Prerequisite: BPK 305 or MBB 308.

An in depth study of the neurophysiology of movement. Illustrates general principles of neural control by exploring specific movement tasks including standing, walking, reaching/grasping, and eye movements. Prerequisite: BPK 306 or BISC 305.

A complex systems lens is used to study the causes, complications and comorbidities of obesity, including diabetes and cardiovascular disease. The etiology of obesity is explored from genetics to environment, including the neuroendocrine biology of appetite regulation. Lifestyle, medical and pharmacological obesity management options and challenges are examined. Prerequisite: BPK 306, 340. Recommended: BPK 110.

Selected topics in areas not currently offered as formal courses within the undergraduate course offerings in the Department of Biomedical Physiology and Kinesiology. The topics in this course will vary from term to term, depending on faculty availability and student interest. Prerequisite: To be announced in the Undergraduate Schedule of Classes and Examinations found at go.sfu.ca.

Selected topics in areas not currently offered as formal courses within the undergraduate course offerings in the Department of Biomedical Physiology and Kinesiology. The topics in this course will vary from term to term, depending on faculty availability and student interest. Prerequisite: To be announced in the Undergraduate Schedule of Classes and Examinations found at go.sfu.ca.

Selected topics in areas not currently offered as formal courses within the undergraduate course offerings in the Department of Biomedical Physiology and Kinesiology. The topics in this course will vary from term to term, depending on faculty availability and student interest. Prerequisite: To be announced in the Undergraduate Schedule of Classes and Examinations found at go.sfu.ca.

Selected topics in areas not currently offered as formal courses within the undergraduate course offerings in the Department of Biomedical Physiology and Kinesiology. The topics in this course will vary from term to term, depending on faculty availability and student interest. Prerequisite: To be announced in the Undergraduate Schedule of Classes and Examinations found at go.sfu.ca.

Students will critically assess and investigate functional neuroanatomy, and examine how neuroimaging, animal models, and functional deficits in patients inform this knowledge. The course encompasses divisions of the human nervous system from both functional (sensory, motor, and autonomic) and anatomical (peripheral and central) perspectives, including the neural basis of higher cortical functions. Prerequisite: BPK 326. Corequisite: BPK 306. BPK 306 is recommended to be completed prior to enrolling in BPK 426.

Core concepts in cancer biology ranging from the clinical and pathological basis of carcinogenesis to the molecular and cellular changes involved in cancer development. Emphasis will be on the complex interactions of lifestyle factors, genetics and social cultural determinants on cancer risk. Prerequisite: MBB 231 (or MBB 201) and at least 90 units.

The study of human temperature regulation in extreme environments. Physiological responses in hot and cold environments will be studied at molecular, cellular and whole body/systems physiology levels. The course focuses on the mechanisms of control of human temperature as well as unresolved topics in this area of physiology. Prerequisite: BPK 305 or BISC 305. Recommended: BPK 407. Students with credit for BPK 420, Physiological Basis of Temperature Regulation, may not take this course for further credit.

Examines the etiology, prevention, and rehabilitation of cardiovascular disease. Involves the assessment of patient risk factors, and non-invasive cardiovascular assessments. Particular emphasis will be placed upon the recording and interpretation of the electrocardiogram in health and disease. Prerequisite: BPK 305. Recommended: BPK 110, 306, 310 and 343.

Examines neural and neuromuscular diseases, including Alzheimer's disease, amyotrophic lateral sclerosis, multiple sclerosis, stroke, and myasthenia gravis. Emphasizes currently favoured hypotheses, underlying evidence and pathogenic mechanisms. Prerequisite: BPK 306. Recommended: BPK 336 and/or BPK 415.

Explores how plasticity of the mammalian brain affects development, learning and adaptation, e.g. to blindness, poverty, stress and technology. Reading 2-4 scientific papers/week, students will learn about important context like peer review and strengthen their ability to read and communicate like a scientist. Prerequisite: BPK 306 or BISC 305. Students who have taken BPK 423 Neuroplasticity may not take this course for further credit.

This course is aimed at students interested in neuromuscular rehabilitation. Students will learn about movement disorders associated with disease or trauma that cause impaired function of sensory and motor systems. The course will be focused on the stages and strategies for recovery of voluntary control of essential functions. The range of rehabilitation interventions available to assist recovery and restore voluntary control will be explored, with special emphasis on advanced techniques to restore control of movement and bodily functions in paralyzed people. Prerequisite: BPK 201 or 207, and BPK 306, or for biomedical engineering students, BPK 201 and 208.

A laboratory based examination of human physiological systems during exposure to aerospace related conditions of altered atmospheric content and G-forces. Developments of breathing apparatus, pressurized flight suits and anti-G-suits for high performance aircraft will be examined as they relate to solving the physiological problems of exposure to these environments. The effects of weightlessness during spaceflight will also be explored through lecture, literature review and current research data. An investigation of the biomedical monitoring of pilots and astronauts will be explored as they relate to health and safety. Prerequisite: BPK 305 or 308. Quantitative.

Directed reading and literature research on topics selected in consultation with the supervising instructor. A short proposal of the project, approved by the course supervisor, must be submitted for approval to the chair of the undergraduate program committee by the end of the first week of classes of the term. May be repeated once for credit with a different course supervisor. Prerequisite: BPK 304W (may be taken concurrently) or PSYC 210, and permission from the chair of the undergraduate program committee. Usually, upper level standing with at least 75 units in the Biomedical Physiology and Kinesiology program will be required.

Directed study and research selected in consultation with the supervising instructor. A short proposal of the project approved by the course supervisor, must be submitted for approval to the chair of the undergraduate program committee by the end of the first week of classes of the term. May be repeated once for credit with a different course supervisor. Prerequisite: BPK 304W (may be taken concurrently) or PSYC 210, and permission from the chair of the undergraduate program committee. Usually, upper level standing with at least 75 units in the Biomedical Physiology and Kinesiology program will be required.