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Discussion of recent literature through student seminars and written reports. Introduction to professional skills for scientific careers.

Oral presentation and defense of a written PhD research proposal. Students will be examined on their knowledge relevant to the proposed research, capacity to complete the proposed thesis research (including any relevant preliminary results), and understanding of the broader field of study. All PhD students enrolled in the MBB PhD graduate program must take MBB 806. Prerequisite: Permission of the student's supervisory committee.

Graded on a satisfactory/unsatisfactory basis.

Discussion of recent literature through student seminars and written reports. Introduction to professional skills for scientific careers.

Recent research articles on the molecular mechanisms underlying cellular activities will be presented and discussed by students and faculty, with an emphasis on critically analyzing concepts, experimental design, and methodology. A student may not take more than 3 units of colloquia for credit. Prerequisite: BISC 331/MBB 331 or equivalent.

Recent research articles on modern genomic techniques will be presented and discussed by students and faculty, with an emphasis on critical analysis of the concepts, experimental design, technologies and the practical application of bioinformatics algorithms. A student may not take more than 3 units of colloquia. Prerequisite: It is recommended that students have previously taken one introductory computer-programming course (e.g. CMPT 102, 110, 120, 130 or equivalent) and one introductory statistics course (e.g. STAT 201, 270 or equivalent); or permission of the instructor.

Recent research articles on the structure, function, and interactions of macromolecules including proteins, nucleic acids, and lipids, as well as their complexes, will be presented and discussed by students and faculty, with an emphasis on critical analysis of the concepts and experimental design and methods. Prerequisite: BISC 331/MBB 331 or equivalent.

Oral presentation and defense of a written PhD research proposal. Students will be examined on their knowledge relevant to the proposed research, capacity to complete the proposed thesis research (including any relevant preliminary results), and understanding of the broader field of study. All PhD students enrolled in the MBB PhD graduate program must take MBB 806. Prerequisite: Permission of the student's supervisory committee.

Graded on a satisfactory/unsatisfactory basis.

Discussion of recent literature through student seminars and written reports. Introduction to professional skills for scientific careers.

This course covers the biology and epidemiology of cancer and theories behind prevention, diagnosis and treatment of different types of cancer. A major goal of the course is to integrate knowledge and research on the biology of cancer with all disciplines in oncology. This course can only be taken once, either during an MSc or during a PhD. Prerequisite: Enrollment in a participating graduate program. No specific courses are prerequisites.

This course features cancer-related research by trainees and faculty at the BC Cancer Research Centre. Topics include recent developments in the molecular basis of oncogenesis, cancer bioinformatics, cancer epidemiology, cancer treatment and other clinical studies, and ethical issues. Students are required to present seminars on their research. Students undertaking the Interdisciplinary Oncology Graduate Specialization must enroll in this course throughout their entire time as a graduate student. This course can be taken twice, if a student does the Interdisciplinary Oncology Graduate Specialization (IOGS) as an MSc student, and also does it as a PhD student. Students who transfer from MSc to PhD would only take it once. Graded on a satisfactory/unsatisfactory basis. Prerequisite: Enrollment in a participating graduate program. No specific courses are prerequisites.

Oral presentation and defense of a written PhD research proposal. Students will be examined on their knowledge relevant to the proposed research, capacity to complete the proposed thesis research (including any relevant preliminary results), and understanding of the broader field of study. All PhD students enrolled in the MBB PhD graduate program must take MBB 806. Prerequisite: Permission of the student's supervisory committee.

Graded on a satisfactory/unsatisfactory basis.

Discussion of recent literature through student seminars and written reports. Introduction to professional skills for scientific careers.

This course covers the biology and epidemiology of cancer and theories behind prevention, diagnosis and treatment of different types of cancer. A major goal of the course is to integrate knowledge and research on the biology of cancer with all disciplines in oncology. This course can only be taken once, either during an MSc or during a PhD. Prerequisite: Enrollment in a participating graduate program. No specific courses are prerequisites.

This course features cancer-related research by trainees and faculty at the BC Cancer Research Centre. Topics include recent developments in the molecular basis of oncogenesis, cancer bioinformatics, cancer epidemiology, cancer treatment and other clinical studies, and ethical issues. Students are required to present seminars on their research. Students undertaking the Interdisciplinary Oncology Graduate Specialization must enroll in this course throughout their entire time as a graduate student. This course can be taken twice, if a student does the Interdisciplinary Oncology Graduate Specialization (IOGS) as an MSc student, and also does it as a PhD student. Students who transfer from MSc to PhD would only take it once. Graded on a satisfactory/unsatisfactory basis. Prerequisite: Enrollment in a participating graduate program. No specific courses are prerequisites.

Recent research articles on the molecular mechanisms underlying cellular activities will be presented and discussed by students and faculty, with an emphasis on critically analyzing concepts, experimental design, and methodology. A student may not take more than 3 units of colloquia for credit. Prerequisite: BISC 331/MBB 331 or equivalent.

Recent research articles on modern genomic techniques will be presented and discussed by students and faculty, with an emphasis on critical analysis of the concepts, experimental design, technologies and the practical application of bioinformatics algorithms. A student may not take more than 3 units of colloquia. Prerequisite: It is recommended that students have previously taken one introductory computer-programming course (e.g. CMPT 102, 110, 120, 130 or equivalent) and one introductory statistics course (e.g. STAT 201, 270 or equivalent); or permission of the instructor.

Recent research articles on the structure, function, and interactions of macromolecules including proteins, nucleic acids, and lipids, as well as their complexes, will be presented and discussed by students and faculty, with an emphasis on critical analysis of the concepts and experimental design and methods. Prerequisite: BISC 331/MBB 331 or equivalent.

Review of basic processes in cell biology including, but not limited to, cell adhesion/migration, cytoskeleton, endo/exocytosis, intracellular trafficking, signal transduction, ion homeostasis, energy generation, protein processing/apoptosis, post-translation modifications, genomics. A review of each topic will be followed by an introduction to cutting-edge work in this field. Prerequisite: Permission of the course co-ordinator.

This class will integrate current knowledge on the process of carcinogenesis in tissues in which cancer commonly occurs in North America. Discussions will focus on new techniques being developed to identify individuals at risk for cancer and new approaches being used to intervene to prevent development of the disease. Prerequisite: BPK (or KIN) 431.

Discussion of novel and advanced topics in chemical covalent modifications of chromatin that influence gene regulation. Prerequisite: MBB 331 or permission from the instructor.

Topics in molecular biology-based research into pathologies of disease related to drug and environmental exposures will be discussed. Focus on systems pharmacology and the molecular determinants of drug and toxicant action as they relate to gene expression and signal transduction.

Application of modern molecular methods to epidemiological questions. Globally-relevant and emerging infectious diseases will be highlighted. The course will emphasize critical review of the current literature in the field. Prerequisite: BISC 303, 330, MBB 331, or permission from the instructor.

An examination of the molecular mechanisms that contribute to tumor formation, the hallmarks of cancer and their relationship to therapeutic strategies.

The organization of the human genome and the role of genomic variation in health and disease. Genomics and personalized medicine; intellectual property and privacy issues.

This course allows students to gain hands-on experience by rotations through specialty laboratories and/or by shadowing clinicians. Students can use the rotation opportunity to learn new techniques and or gain an understanding of the clinical aspects of their research project. The supervisor and supervisory committee create a custom rotation plan for the student. A grade is assigned based on a written report by the student, which is evaluated by the student's supervisory committee. This course can only be taken once, either during an MSc or during a PhD. Prerequisite: Enrollment in a participating graduate program. No specific courses are prerequisites. Permission from instructor required.

Oral presentation and defense of a written PhD research proposal. Students will be examined on their knowledge relevant to the proposed research, capacity to complete the proposed thesis research (including any relevant preliminary results), and understanding of the broader field of study. All PhD students enrolled in the MBB PhD graduate program must take MBB 806. Prerequisite: Permission of the student's supervisory committee.

Graded on a satisfactory/unsatisfactory basis.

Covers fundamental concepts related to the basic cellular neurobiology of neurons and other nervous system cells, neuronal pathfinding, electrophysiology, dendritic organization, axonal transport, plasticity, and signal transduction, as well as the integration of neurons into neural circuits and diseases of the nervous system. This course can only be taken once, either during a Masters or Doctoral program.

Fundamental concepts related to information processing (sensing, encoding, planning, decision-making, execution) by neural circuits are discussed. Topics include: neural communication, sensorimotor control of movement, neuroplasticity, and diseases of the brain. Issues of experimental design and application of modern neuroscience methods will be integrated across these topics. Additional topics will vary depending on the year. This course can only be taken once, either during a Masters or Doctoral program.

Workshops focus on providing students with skills to facilitate the translation of neuroscience, broadly defined, for the benefit of society. Faculty members at ¶¡ÏãÔ°AV as well as relevant clinicians and company representatives will run these workshops. Topics may include: how to translate fundamental questions into clinical-oriented questions; how to perform clinical research; how to start a spin-off company; how to pitch ideas for commercialization; how to work with industry; how drug-discovery works; and how to communicate to different audiences. All topics will relate specifically to neuroscience. Graded on a satisfactory/unsatisfactory basis. Prerequisite: Enrollment in translational and integrative neuroscience graduate specialization or permission from lead workshop organizer.