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An introduction to the biochemical and physiological mechanisms of living organisms. Topics covered include cell structure and function, DNA replication and the flow of genetic information, enzyme function, metabolism and physiology of microorganisms, plants, and animals. Prerequisite: High school Biology 12 (or equivalent) with a C grade or better, or BISC 100 with C- or better, or BISC 113 with C+ or better, or HSCI 100 with C+ or better; and High school Chemistry 12 (or equivalent) with a C grade or better, or CHEM 111 with a C- or better. Breadth-Science.

Survey of the diversity of life, and its evolutionary history on earth. The student is introduced to the study of genetics, development, and evolution, giving an overview of how these processes interact to produce form and function. Also included are principles of behavior and ecological relationships of organisms to each other and their environment. Prerequisite: High school biology 12 (or equivalent) with a C grade or better, or BISC 100 with C- or better, or BISC 113 with C+ or better, or HSCI 100 with C+ or better. Breadth-Science.

Principles and concepts of the transmission of genetic information treated comparatively in man, animal, plant and microbe. Prerequisite: BISC 101 and 102 with a grade of C- or better.

Structure, bonding, physical and chemical properties of simple organic compounds. Introduction to spectroscopy. Kinetics and mechanisms of organic reactions. This course includes a laboratory component. Prerequisite: CHEM 121. Corequisite: CHEM 122. Quantitative.

Polyfunctional organic compounds and complex organic reactions. Introduction to natural products. Students with credit for CHEM 283 may not complete this course for further credit. Prerequisite: CHEM 281. Quantitative.

Rectangular, cylindrical and spherical coordinates. Vectors, lines, planes, cylinders, quadric surfaces. Vector functions, curves, motion in space. Differential and integral calculus of several variables. Vector fields, line integrals, fundamental theorem for line integrals, Green's theorem. Prerequisite: MATH 152; or MATH 155 or MATH 158 with a grade of at least B. Recommended: It is recommended that MATH 240 or 232 be taken before or concurrently with MATH 251. Quantitative.

Vector calculus, divergence, gradient and curl; line, surface and volume integrals; conservative fields, theorems of Gauss, Green and Stokes; general curvilinear coordinates and tensor notation. Introduction to orthogonality of functions, orthogonal polynomials and Fourier series. Prerequisite: MATH 240 or 232, and 251. MATH 240 or 232 may be taken concurrently. Students with credit for MATH 254 may not take MATH 252 for further credit. Quantitative.

The structure, function and synthesis of proteins, RNA and DNA and their interrelated biological functions within the cell. An introduction to molecular biology techniques and methods of protein purification and analysis. Prerequisite: or Corequisite CHEM 281.

A study of the molecular processes which underlie cell structure and function, integrating ultrastructural, physiological and biochemical approaches. Modern techniques used in the analysis of organelle and cell function are integral parts of the course. Prerequisite: MBB 222, BISC 101, CHEM 281 with grades of C- or better. Corequisite or Prerequisite: CHEM 282 or CHEM 283.

A seminar to expose students majoring in any Physics program to opportunities available with a physics degree. Seminar will include invited speakers, group discussions, and student presentations on topics including modern physics research, industrial physics, career opportunities, and communication and other professional skills. May be repeated once for credit. Graded as pass/fail (P/F). Prerequisite: PHYS 121 or 126 or PHYS 141, (or PHYS 102 with a minimum grade of B).

An intermediate mechanics course covering kinematics, dynamics, calculus of variations and Lagrange's equations, non-inertial reference frames, central forces and orbits, and rigid body motion. Prerequisite: PHYS 126 or 121 or 141, with a minimum grade of C- (or PHYS 102 with a minimum grade of B). Corequisite: MATH 251; MATH 232 or 240. Recommended: MATH 310 and PHYS 255. Quantitative.

Introduction to modern techniques in experimental physics, including computer-aided data acquisition, electronics, control theory, and statistical data analysis. Prerequisite: PHYS 130, 133 or 141 (no substitutions). Co-requisite: PHYS 255. Quantitative.

The physics of vibrations and waves. Topics include periodic motion, including free and forced oscillations, coupled oscillators, normal modes, and waves in one and higher dimensions. Prerequisite: PHYS 126 or 121 or 141 with a minimum C- grade; or PHYS 101 and 102 with a grade of B or better. Corequisite: MATH 251; MATH 232 or 240. Recommended concurrent: PHYS 211 and MATH 310. Quantitative.

Atomic and molecular structure; chemical bonding; thermochemistry; elements; periodic table; gases liquids, solids, and solutions. This course includes a laboratory component. Prerequisite: BC high school chemistry 12 or CHEM 109 or CHEM 111. Students may not count both CHEM 120 and 121 for credit. Quantitative/Breadth-Science.

An enriched chemistry course, covering atomic and molecular structure; chemical bonding; thermochemistry; elements; periodic table; gases, liquids, solids, and solutions, focusing on current chemistry research and applications. The topics will be covered with more sophistication than in other 1st year chemistry courses, and thus a thorough mastery of high-school chemistry will be assumed. This course includes a laboratory component. Prerequisite: By permission of the Department. BC high school chemistry 12 or CHEM 111. Students may not count more than one of CHEM 120, 121 or 123 for credit. Recommended: MATH 125 (or 151 or 154) and PHYS 125 (or 120 or 101) as a corequisite. Quantitative.

Chemical equilibria; electrochemistry; chemical thermodynamics; kinetics. Students who intend to take further laboratory courses in chemistry should take CHEM 122 concurrently with CHEM 126. Prerequisite: CHEM 121 or 120. Recommended: MATH 152 (or 155) and PHYS 121 (or 102) as a corequisite. Quantitative.

An enriched chemistry course, covering chemical equilibria; electrochemistry; chemical thermodynamics; kinetics, energy and nuclear science, focusing on current chemistry research and applications. The topics will be covered with more sophistication than in other 1st year chemistry courses, and thus a thorough mastery of high-school chemistry will be assumed. Prerequisite: CHEM 123; or CHEM 121 (or 120) and permission of the Department. Students may not count more than one of CHEM 122 or 124 for credit. Corequisite: Students who intend to take further laboratory courses in chemistry should take CHEM 124 concurrently with CHEM 126. Recommended: MATH 126 (or 152 or 155) and PHYS 126 (or 121 or 102) as a corequisite. Quantitative.

Review of limits and differentiation. Complex numbers and link to polar coordinates. Mathematics of kinematics, including vectors and parametrics curves. Area and Riemann sums. Definite and indefinite integration. Fundamental Theorems of Calculus. Techniques of integration and approximation of integrals. Series and tests of convergence. Taylor series. Solution of first and constant-coefficient second order ODE. Prerequisite: MATH 150 or MATH 151 or MATH 154 with a grade of at least B or IB Mathematics HL with a score of 6 or better or AP Calculus AB or BC with a grade of at least 4, or BC Calculus 12 and a pass on the Calculus Challenge Exam. And Permission of the Department. Recommended corequisite: Physics 125.

Designed for students specializing in mathematics, physics, chemistry, computing science and engineering. Topics as for Math 151 with a more extensive review of functions, their properties and their graphs. Recommended for students with no previous knowledge of Calculus. In addition to regularly scheduled lectures, students enrolled in this course are encouraged to come for assistance to the Calculus Workshop (Burnaby), or Math Open Lab (Surrey). Prerequisite: Pre-Calculus 12 (or equivalent) with a grade of at least B+, or MATH 100 with a grade of at least B-, or achieving a satisfactory grade on the ¶¡ÏãÔ°AV Calculus Readiness Test. Students with credit for either MATH 151, 154 or 157 may not take MATH 150 for further credit. Quantitative.

Designed for students specializing in mathematics, physics, chemistry, computing science and engineering. Logarithmic and exponential functions, trigonometric functions, inverse functions. Limits, continuity, and derivatives. Techniques of differentiation, including logarithmic and implicit differentiation. The Mean Value Theorem. Applications of differentiation including extrema, curve sketching, Newton's method. Introduction to modeling with differential equations. Polar coordinates, parametric curves. Prerequisite: Pre-Calculus 12 (or equivalent) with a grade of at least A, or MATH 100 with a grade of at least B, or achieving a satisfactory grade on the ¶¡ÏãÔ°AV Calculus Readiness Test. Students with credit for either MATH 150, 154 or 157 may not take MATH 151 for further credit. Quantitative.

Partial differentiation and applications. Taylor series of functions of two variables. Method of characteristics for 1-D transport and wave equations. Similarity solutions including plane waves, traveling waves and scaling solutions, with applications in the physical sciences. Introduction to vector calculus, including differentiation, decompositions via potentials. Curvilinear coordinate systems. Multivariate integration, including Green's, the Stokes and the Divergence theorem. Introduction to abstract vector spaces. Linear independence. Inner products and orthogonality. Fourier Series. Prerequisite: A grade of C+ or higher in Math 125 or Math 152. And Permission of the Department. Recommended corequisite: Physics 126.

Riemann sum, Fundamental Theorem of Calculus, definite, indefinite and improper integrals, approximate integration, integration techniques, applications of integration. First-order separable differential equations and growth models. Sequences and series, series tests, power series, convergence and applications of power series. Prerequisite: MATH 150 or 151; or MATH 154 or 157 with a grade of at least B. Students with credit for MATH 155 or 158 may not take this course for further credit. Quantitative.

Linear equations, matrices, determinants. Introduction to vector spaces and linear transformations and bases. Complex numbers. Eigenvalues and eigenvectors; diagonalization. Inner products and orthogonality; least squares problems. An emphasis on applications involving matrix and vector calculations. Prerequisite: MATH 150 or 151; or MACM 101; or MATH 154 or 157, both with a grade of at least B. Students with credit for MATH 240 make not take this course for further credit. Quantitative.

Linear equations, matrices, determinants. Real and abstract vector spaces, subspaces and linear transformations; basis and change of basis. Complex numbers. Eigenvalues and eigenvectors; diagonalization. Inner products and orthogonality; least squares problems. Applications. Subject is presented with an abstract emphasis and includes proofs of the basic theorems. Prerequisite: MATH 150 or 151; or MACM 101; or MATH 154 or 157, both with a grade of at least B. Students with credit for MATH 232 cannot take this course for further credit. Quantitative.

Elements of physical chemistry from the molecular point of view. Introduction to quantum chemistry, atomic and molecular structure, and spectroscopy. Prerequisite: CHEM 122, MATH 152, PHYS 102 (with at least a B grade) or PHYS 121 or PHYS 126 or PHYS 141. Recommended: MATH 232. Quantitative.

Special relativity, including relativistic kinematics and dynamics; tests of relativity; matter waves and early quantum models; wave mechanics and its application to molecular, atomic and subatomic systems. Prerequisite: PHYS 255, with a minimum grade of C-. Quantitative.

Force and motion, conservation of energy and momentum, fluids, properties of soft matter and thermal physics with applications taken from the life sciences. Prerequisite: BC Principles of Physics 12 or PHYS 100 or equivalent, with a minimum grade of C-. This prerequisite may be waived, at the discretion of the department, as determined by the student's performance on a regularly scheduled PHYS 100 final exam. Please consult the physics advisor for further details. Corequisite: MATH 150 or 151 or 154 or 157; BISC 100 or 101 or 102. Recommended Corequisite: PHYS 132. Students with credit for PHYS 120, 125 or 140 may not take this course for further credit. Quantitative/Breadth-Science.

A general calculus-based introduction to mechanics. Topics include translational and rotational motion, momentum, energy, gravitation, and selected topics in modern physics. Prerequisite: BC Principles of Physics 12 or PHYS 100 or equivalent, with a minimum grade of C-. This prerequisite may be waived, at the discretion of the department, as determined by the student's performance on a regularly scheduled PHYS 100 final exam. Please consult the physics advisor for further details. Corequisite: MATH 150 or 151 or 154 must precede or be taken concurrently. Students with credit for PHYS 101, 125 or 140 may not take this course for further credit. Quantitative/Breadth-Science.

An enriched course in mechanics for students with good preparation in physics and mathematics. Special relativity and classical topics such as translational and rotational dynamics and conservation laws will be given a much more sophisticated treatment than in our other first-year courses. Prerequisite: Permission of the department. Co-requisite: MATH 125 or MATH 151. Students with credit for PHYS 101, 120 or PHYS 140 may not take PHYS 125 for further credit. Quantitative.

A general calculus-based introduction to mechanics taught in an integrated lecture-laboratory environment. Topics include translational and rotational motion, momentum, energy, gravitation, and selected topics in modern physics. Prerequisite: BC Principles of Physics 12, or PHYS 100 or equivalent, with a minimum grade of C-. Corequisite: MATH 150 or 151 or 154 must precede or be taken concurrently. Students with credit for PHYS 125 or 120 or 101 may not take this course for further credit. Quantitative/Breadth-Science.

Waves and optics; electricity and magnetism; modern physics emphasizing radioactivity, with applications taken from the life sciences. Prerequisite: PHYS 101 or 120 or 125 or 140 and MATH 154 or 150 or 151 or 157, all with a minimum grade of C-. Corequisite: BISC 100 or 101 or 102. Recommended Corequisites: MATH 152, 155 or 158, and PHYS 133. Students with credit for PHYS 121, 126, or 141 may not take this course for further credit. Quantitative/Breadth-Science.

A general calculus-based introduction to electricity, magnetism and optics. Topics include electricity, magnetism, simple circuits, optics and topics from applied physics. Prerequisite: PHYS 120 or 125 or 140 (or PHYS 101 with a grade of A or B). Corequisite: MATH 152 or 155 must precede or be taken concurrently. Students with credit for PHYS 102, 126 or 141 may not take this course for further credit. Quantitative/Breadth-Science.

An enriched course in electromagnetism for students with good preparation in physics and mathematics. Classical topics such as waves, electricity and magnetism, as well as wave particle duality and the birth of Quantum Mechanics, will be given a much more sophisticated treatment than in our other first year courses. Prerequisite: PHYS 125 and permission of the department. Co-requisite: MATH 126 or MATH 152. Students with credit in PHYS 102, 121 or 141 may not take this course for further credit. Quantitative.

A general calculus-based introduction to electricity, magnetism and optics taught in an integrated lecture-laboratory environment. Topics include electricity, magnetism, simple circuits, optics and topics from applied physics. Prerequisite: PHYS 120 or PHYS 125 or PHYS 140, with a minimum grade of C- (or PHYS 101 with a minimum grade of B). Corequisite: MATH 152 or 155 must precede or be taken concurrently. Students with credit for PHYS 126 or 121 or 102 may not take this course for further credit. Quantitative/Breadth-Science.

Elementary experiments in optics, electricity, mechanics and heat that are designed to augment the general survey course. Corequisite: PHYS 102 should be taken concurrently or may precede; or by permission of the department. Students with credit for PHYS 131, 133, or 141 may not take PHYS 130 for further credit. Quantitative.

Introduction to experimental physics with an emphasis on measurement and experimental design. Includes elementary experiments in mechanics designed to support and enrich conceptual learning. Corequisite: PHYS 120 or 125. Students with credit for PHYS 130, 131, or 140 may not take PHYS 132 for further credit. Quantitative.

Introduction to experimental physics with an emphasis on measurement and experimental design. Includes elementary experiments in electromagnetism and optics designed to support and enrich conceptual learning. Prerequisite: PHYS 132 or 140 or ENSC 120 (no substitutions). Corequisite: PHYS 121 or 126. Students with credit for PHYS 130, 131, or 141 may not take PHYS 133 for further credit. Quantitative.

First-order differential equations, second- and higher-order linear equations, series solutions, introduction to Laplace transform, systems and numerical methods, applications in the physical, biological and social sciences. Prerequisite: MATH 152; or MATH 155/158 with a grade of at least B, MATH 232 or 240. Quantitative.

Biochemical and molecular aspects of cellular function, interactions and communication including cell cycle, apoptosis, cancer, immune system, neuronal transmission and the signal transduction pathways that integrate them. Prerequisite: MBB 231, with a minimum grade of C.

The study of DNA and RNA in relation to gene structure and expression: DNA replication and the regulation of gene expression in bacteria and higher organisms. Introduction to recombinant DNA and cloning theory; natural vector structures and recombinant vector construction. Prerequisite: MBB 231, and BISC 202, with a minimum grade of C.

Development and application of Maxwell's equations in vector differential form. Notation and theorems of vector calculus; electric charge, fields, potentials, capacitance and field energy; conductors; methods for solving electrostatic problems; electric fields in matter; electrical current and the magnetic field; Ampere's law and the vector potential; magnetic fields in matter; electromotive force, electrical resistance, Faraday's law and inductance; Maxwell's correction to Ampere's law and electromagnetic waves. Prerequisite: PHYS 121 or 126 or 141 (or PHYS 102 with a minimum grade of B); MATH 252 or 254; MATH 310, with a minimum grade of C-. Students with credit for PHYS 221 may not take this course for further credit. Quantitative.

Experiments investigating a range of physical phenomena such as Brownian motion, molecular order, chaotic dynamics, Doppler broadening of stellar spectra, and biophysical forces using techniques such as interference, optical trapping, and spectroscopy. Attention will also be given to more general skills, including experimental design, operating and troubleshooting experimental equipment, modeling of experimental results, data analysis, and the presentation of experimental results. Biological Physics students will do a selected set of experiments. Prerequisite: Either PHYS 233 or both (PHYS 231 and either CHEM 266 or PHYS 347) and either PHYS 285 or CHEM 260, all with a minimum grade of C-. PHYS 347 may be taken concurrently. Students with credit for PHYS 332 may not take this course for further credit. Writing/Quantitative.

A physics perspective on cellular structure and composition; random walks and diffusion; properties of fluids, cell motion; entropy and the properties of soft materials; structure and function of proteins; signal propagation in nerves. Prerequisite: Completion of 45 units including CHEM 122, MATH 152 (or 155), PHYS 121 (or 102 or 126 or 141), with a minimum grade of C-. Recommended: BISC 101. Quantitative.

Wave mechanics and the Schroedinger equation, the harmonic oscillator, introduction to Dirac notation, angular momentum and spin, the hydrogen atom, atomic structure, time-independent perturbation theory, atomic spectra, and applications. Prerequisite: MATH 252 or 254; PHYS 285 or ENSC 380 or CHEM 260, with a minimum grade of C-. Corequisite: PHYS 211; MATH 310. Quantitative.

Elements of physical chemistry from the macroscopic point of view. Thermodynamics, and its applications to chemical equilibrium. Chemical kinetics and reaction rate theories. Prerequisite: CHEM 260. Recommended: MATH 251. Credit will not be granted for both CHEM 360 and MBB 323. Quantitative.

Introduction to physical biochemistry including thermodynamics, spectroscopic principles and applications, and molecular transport and interactions. The physical properties and structure determination of biomolecules will be emphasized. Prerequisite: MATH 152 (or 155), PHYS 121 (or 102, or 126, or 141), CHEM 122 (or 102), MBB 222 with a minimum grade of C.

Heat, temperature, heat transfer, kinetic theory, laws of thermodynamics, entropy, heat engines, applications of thermodynamics to special systems, phase transitions. Prerequisite: PHYS 126 or PHYS 121 or PHYS 141, MATH 251. Quantitative.

Modern molecular biological and recombinant nucleic acid methods will be covered. Examples are DNA and RNA isolation, plasmid preparation, restriction enzyme digestion, DNA cloning and polymerase chain reaction. Prerequisite: MBB 331 with a minimum grade of C-. Students with credit for BISC 357 may not take this course for further credit.

Contemporary techniques in biochemistry including protein purification, immunochemical methods, and lipid characterization. Prerequisite: MBB 231, with a minimum grade of C. Recommended: CHEM 215 and CHEM 286 precede MBB 309W. Writing.

Part 1 of a 3-part honours degree program, the individual study semester (ISS). The ISS provides students with the opportunity to carry out full time laboratory research in molecular biology and biochemistry. The grade for MBB 481 encompasses the research design aspect of the ISS, consisting of the honours thesis. Prerequisite: MBB 308, MBB 309W and MBB 331. Enrollment in the MBB or Biological Physics Honours Program, a minimum 3.0 CGPA and 3.0 UDGPA and permission of the MBB department. Corequisite: MBB 482 and MBB 483.

Part 2 of a 3-part honours degree program, the individual study semester (ISS). The ISS provides students with the opportunity to carry out full time laboratory research in molecular biology and biochemistry. The grade for MBB 482 encompasses the research performance aspect of the ISS. Prerequisite: MBB 308, MBB 309W and MBB 331. Enrollment in the MBB or Biological Physics Honours Program, a minimum 3.0 CGPA and 3.0 UDGPA and permission of the MBB department. Corequisite: MBB 481 and MBB 483.

Part 3 of a 3-part honours degree program, the individual study semester (ISS). The ISS provides students with the opportunity to carry out full time laboratory research in molecular biology and biochemistry. The grade for MBB 483 encompasses the defense component of the ISS. Prerequisite: MBB 308, MBB 309W and MBB 331. Enrollment in the MBB or Biological Physics Honours Program, a minimum 3.0 CGPA and 3.0 UDGPA and permission of the MBB department. Corequisite: MBB 481 and MBB 482.

Modern molecular biological and recombinant nucleic acid methods will be covered. Examples are DNA and RNA isolation, plasmid preparation, restriction enzyme digestion, DNA cloning and polymerase chain reaction. Prerequisite: MBB 331 with a minimum grade of C-. Students with credit for BISC 357 may not take this course for further credit.

Contemporary techniques in biochemistry including protein purification, immunochemical methods, and lipid characterization. Prerequisite: MBB 231, with a minimum grade of C. Recommended: CHEM 215 and CHEM 286 precede MBB 309W. Writing.

Part time laboratory research in an area of molecular biology or biochemistry. MBB 491-5 can be taken as a stand-alone course by MBB majors, or as the first of two courses for Option B of an honours thesis. MBB 491 coursework will include the preparation of a research proposal, a report on the results of the project and an oral presentation of the research. Before seeking approval for enrollment in this course, the student should obtain the agreement of an MBB faculty member that he/she is willing to supervise the project and prepare in collaboration with the supervisor, a one-page Letter of Intent stating the nature of the research project. Prerequisite: MBB 308 or MBB 309W and permission of the MBB department. Upper level standing in an MBB major or honours program is required.

Two-thirds of full-time laboratory research in an area of molecular biology or biochemistry. This course is the second of two courses, MBB 491 and MBB 492, taken as Option B of the MBB honours program. It is typically a continuation of a research project that began in MBB 491, under the supervision of the same faculty member. The course will include the preparation of a comprehensive written research report and an oral presentation on the results of the project. Prerequisite: MBB 491, MBB 308, MBB 309W and MBB 331, enrollment in the MBB honours program, a minimum 3.0 CGPA and 3.0 UDGPA and permission of the department.

Applications of mathematical methods in physics, differential equations of physics, eigenvalue problems, solutions to wave equations. Prerequisite: MATH 252 or 254; MATH 310; PHYS 255 or ENSC 320, with a minimum grade of C-. Corequisite: PHYS 211. Quantitative.

Foundations of quantum mechanics, time-dependent perturbation theory, radiation, variational methods, scattering theory, advanced topics, and applications. Prerequisite: PHYS 385 and either PHYS 384 or MATH 314 and 419, with a minimum grade of C-. Quantitative.

A continuation of PHYS 321: properties of electromagnetic waves and their interaction with matter. Transmission lines and waveguides; antennas, radiation and scattering; propagation of electromagnetic waves in free space and in matter; reflection and refraction at boundaries; polarization, interference and diffraction. Prerequisite: PHYS 321 (no substitution); PHYS 255 or ENSC 380. Students with credit for PHYS 324 or 425 may not take PHYS 421 for further credit. Quantitative.

Undergraduate research and preparation of an honours thesis over the fall and the subsequent spring semesters. The research project may be in experimental or theoretical physics. Prospective students must obtain agreement of a faculty member willing to supervise the project. Prerequisite: All students interested in taking this course must consult with their faculty supervisor regarding prerequisites.

Postulates of statistical mechanics, partition functions, applications to gases, paramagnetism and equilibrium. Quantum statistics and applications. Prerequisite: PHYS 344 or CHEM 360, with a minimum grade of C-. Recommended: PHYS 385. Quantitative.

Students are introduced to models and simulations for biological systems at the ecosystem, organismal, cellular, and molecular levels. They will discover how to design and use models, and will then apply these skills to build their own model using basic mathematical tools, Excel, and Matlab. Prerequisite: MATH 150 or 151, and 152 both with a grade of C+ or better, or MATH 154 and 155 both with a grade of B or better; and at least 60 units; or permission of the instructor. Recommended: A 100 level Biology course. Students who have taken Special Topics course BISC 475 "Movement, Molecules, and Models" may not take BISC 421 for further credit. Quantitative.

Incompressible fluid flow phenomena: kinematics and equations of motion, viscous flow and boundary layer theory, potential flow, water waves. Aerodynamics. Prerequisite: one of MATH 314, MATH 418, PHYS 384. An alternative to the above prerequisite is both of MATH 251 and MATH 310, both with grades of at least B+. Quantitative.

Modern molecular biological and recombinant nucleic acid methods will be covered. Examples are DNA and RNA isolation, plasmid preparation, restriction enzyme digestion, DNA cloning and polymerase chain reaction. Prerequisite: MBB 331 with a minimum grade of C-. Students with credit for BISC 357 may not take this course for further credit.

Contemporary techniques in biochemistry including protein purification, immunochemical methods, and lipid characterization. Prerequisite: MBB 231, with a minimum grade of C. Recommended: CHEM 215 and CHEM 286 precede MBB 309W. Writing.

The enzymes and intermediates of major catabolic and anabolic pathways. Their regulation and integration in health and disease states. Prerequisite: MBB 231, with a minimum grade of C.

Major topics in genomics and bioinformatics, with integrated discussion of associated ethical/legal/social issues. An overview of laboratory and computer-based methods to study genomes, and their applications. Hands-on computer lab session providing an opportunity to use and experiment with bioinformatics software and databases utilized in genomics and bioinformatics research. Prerequisite: MBB 231, BISC 202 and 3 units of CMPT or equivalent, with a minimum grade of C. Recommended: STAT 201 (or an equivalent statistics course) or STAT 270.

Recent literature is examined for insights into the structure and properties of DNA and RNA, drawing on a variety of biochemical, chemical and molecular biological perspectives. Prerequisite: MBB 331 with a minimum grade of C.

A review of recent research on the structure, dynamics, function and biosynthesis of membranes, membrane lipids and proteins. Prerequisite: MBB 322 and MBB 309W with a minimum grade of C, MBB 324 as a pre or co-requisite.

Mechanistic principles for how protein molecules achieve diverse functions such as chemical catalysis and conformational switching. Students will learn to critique hypotheses about structural mechanisms, and to interpret the primary literature reporting on structural evidence from X-ray diffraction and spectroscopy. Prerequisite: MBB 323 or MBB 324, with a minimum grade of C.

Computer-based approaches to solving complex physical problems. Includes topics such as Monte-Carlo and molecular dynamics techniques applied to thermal properties of materials; dynamical behavior of systems, including chaotic motion; methods for ground state determination and optimization, including Newton-Raphson, simulated annealing, neural nets, and genetic algorithms: symplectic methods; and analysis of numerical data. Prerequisite: MATH 310, PHYS 255, CMPT 102, 120, or equivalent, with a minimum grade of C-. Recommended: PHYS 344 or equivalent. Quantitative.

Central forces, rigid body motion, small oscillations. Lagrangian and Hamiltonian formulations of mechanics. Prerequisite: PHYS 384, with a minimum grade of C- or permission of the department. Non-physics majors may enter with MATH 252, 310 and PHYS 211, with a minimum grade of C-. Quantitative.

Postulates of statistical mechanics, partition functions, applications to gases, paramagnetism and equilibrium. Quantum statistics and applications. Prerequisite: PHYS 344 or CHEM 360, with a minimum grade of C-. Recommended: PHYS 385. Quantitative.

Optical physics, including geometrical and physical optics, waves in anisotropic media, coherence, image formation and Fourier optics, guided wave optics and selected advanced topics such as lasers, nonlinear optics, photonics and quantum optics. Prerequisite: PHYS 321 or 221, with a minimum grade of C-. Corequisite: PHYS 385. Quantitative.

Studies in areas not included within the undergraduate course offerings of the Department of Physics. Prerequisite: Permission of the department.