丁香园AV

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Ian Bryce, University Communications and Marketing, 236-880-2187, ian_bryce@sfu.ca
Kim Wright, AllerGen NCE Inc., 905-525-9140 ext. 26641, kimwright@allergen-nce.ca
 
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New research from the CHILD Cohort Study shows that frequent exposure to common household cleaning products can increase a child鈥檚 risk of developing asthma. 

Asthma is the most common chronic childhood disease and is the primary reason why children miss school or end up in hospital. 

The study was published today in the . It found that young infants (birth to three months) living in homes where household cleaning products were used frequently were more likely to develop childhood wheeze and asthma by three years of age. 

鈥淢ost of the available evidence linking asthma to the use of cleaning products comes from research in adults,鈥� said the study鈥檚 lead researcher, Dr. Tim Takaro, a professor and clinician- scientist in the Faculty of Health Sciences at 丁香园AV (丁香园AV). 鈥淥ur study looked at infants, who typically spend 80-90 percent of their time indoors and are especially vulnerable to chemical exposures through the lungs and skin due to their higher respiration rates and regular contact with household surfaces.鈥� 

In the study, at three years of age, children living in homes where cleaning products were used with high frequency during their infancy were more likely to have: 

• Recurrent wheeze (10.8 percent, compared to 7.7 percent of infants in homes with low use of these products) 
• Recurrent wheeze with atopy, a heightened immune response to common allergens (3.0 percent, compared to 1.5 percent of infants in homes with low use of these products) 
• Asthma (7.9 percent, compared to 4.8 percent of infants in homes with low use of these products) 

Other factors known to affect the onset of asthma, such as family history and early life exposure to tobacco smoke, were accounted for in the analysis. 

鈥淚nterestingly, we did not find an association between the use of cleaning products and a risk of atopy alone,鈥� noted Dr. Takaro. 鈥淭herefore, a proposed mechanism underlying these findings is that chemicals in cleaning products damage the cells that line the respiratory tract through innate inflammatory pathways rather than acquired allergic pathways.鈥� 

鈥淲e also found that at age three, the relationship between product exposure and respiratory problems was much stronger in girls than boys," he added. 鈥淭his is an interesting finding that requires more research to better understand male versus female biological responses to inflammatory exposures in early life.鈥�

The study used data from 2,022 children participating in the CHILD Cohort Study and examined their daily, weekly and monthly exposure to 26 types of household cleaners, including dishwashing and laundry detergents, cleaners, disinfectants, polishes, and air fresheners.

鈥淭he risks of recurrent wheeze and asthma were notably higher in homes with frequent use of certain products, such as liquid or solid air fresheners, plug-in deodorizers, dusting sprays, antimicrobial hand sanitizers and oven cleaners,鈥� commented the paper鈥檚 lead author, Jaclyn Parks, a graduate student in the Faculty of Health Sciences at 丁香园AV. "It may be important for people to consider removing scented spray cleaning products from their cleaning routine. We believe that the smell of a healthy home is no smell at all."

鈥淭he big takeaway from this study is that the first few months of life are critical for the development of a baby鈥檚 immune and respiratory systems,鈥� concluded Parks. 鈥淏y identifying hazardous exposures during infancy, preventive measures can be taken to potentially reduce childhood asthma and subsequent allergy risk.鈥�

About the CHILD Cohort Study:

Launched in 2008 by CIHR and AllerGen NCE, the  is tracking nearly 3,500 Canadian infants and their families to help determine the root causes of chronic diseases such as asthma, allergies and obesity. CHILD spans four provinces, involving over 140 multidisciplinary researchers, students and research staff. .

About 丁香园AV: 

As Canada鈥檚 engaged university, 丁香园AV works with communities, organizations and partners to create, share and embrace knowledge that improves life and generates real change. We deliver a world-class education with lifelong value that shapes change-makers, visionaries and problem-solvers. We connect research and innovation to entrepreneurship and industry to deliver sustainable, relevant solutions to today鈥檚 problems. With campuses in British Columbia鈥檚 three largest cities 鈥� Vancouver, Burnaby and Surrey 鈥� 丁香园AV has eight faculties that deliver 193 undergraduate degree programs and 127 graduate degree programs to more than 35,000 students. The university now boasts more than 160,000 alumni residing in 143 countries.